2,2-DIMETHYLSUCCINIC ACID

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H10O4
Molecular Weight	146.1412
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)(CC(O)=O)C(O)=O

InChI

InChIKey=GOHPTLYPQCTZSE-UHFFFAOYSA-N

InChI=1S/C6H10O4/c1-6(2,5(9)10)3-4(7)8/h3H2,1-2H3,(H,7,8)(H,9,10)

HIDE SMILES / InChI

Molecular Formula	C6H10O4
Molecular Weight	146.1412
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Nutrient withdrawal rescues growth factor-deprived cells from mTOR-dependent damage.	2010-08	20739737
Pyruvate dehydrogenase kinase 1 controls mitochondrial metabolism and insulin secretion in INS-1 832/13 clonal beta-cells.	2010-07-01	20415663
Thermodynamic and kinetic control on the formation of two novel metal-organic frameworks based on the Er(III) ion and the asymmetric dimethylsuccinate ligand.	2010-06-07	20429519
catena-Poly[[diaqua-cadmium(II)]bis-(μ-2,2-dimethyl-butane-dioato-κO,O':O'',O''')[diaqua-cadmium(II)]-μ-1,4-bis-(3-pyridylmeth-yl)piperazine-κN:N].	2010-05-26	21579341
(E)-2-(Cyclo-hexyl-methyl-ene)succinic acid.	2007-12-21	21200897
Hypoxia stabilizes type 2 deiodinase activity in rat astrocytes.	2007-10	17615150
A new strategy for the synthesis of taurine derivatives using the 'safety-catch' principle for the protection of sulfonic acids.	2007-01-07	17164917
Structural characterization of anti-HIV drug candidate PA-457 [3-O-(3',3'-dimethylsuccinyl)-betulinic acid] and its acyl glucuronides in rat bile and evaluation of in vitro stability in human and animal liver microsomes and plasma.	2006-09	16751262
Intermediates of Krebs cycle correct the depression of the whole body oxygen consumption and lethal cooling in barbiturate poisoning in rat.	2004-10-01	15337580
A sensitive method for 4-hydroxybutyric acid in urine using gas chromatography-mass spectrometry.	2003-07-15	12829007
Cancer chemopreventive effect of quassinoid derivatives. Introduction of side chain to shinjulactone C for enhancement of inhibitory effect on Epstein-Barr virus activation.	2002-11-08	12142078
The renal Na(+)-dependent dicarboxylate transporter, NaDC-3, translocates dimethyl- and disulfhydryl-compounds and contributes to renal heavy metal detoxification.	2002-11	12397032
Rapid and sensitive detection of urinary 4-hydroxybutyric acid and its related compounds by gas chromatography-mass spectrometry in a patient with succinic semialdehyde dehydrogenase deficiency.	2002-08-25	12127325
Cloning and functional characterization of a high-affinity Na(+)/dicarboxylate cotransporter from mouse brain.	2001-05	11287335

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:08:52 GMT 2025` Edited by `admin` on `Mon Mar 31 21:08:52 GMT 2025`
Record UNII	MX6TVR2107
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

2,2-DIMETHYLSUCCINIC ACID

Systematic Name

English

NSC-408419

Preferred Name

English

SUCCINIC ACID, .ALPHA.,.ALPHA.-DIMETHYL-

Common Name

English

2,2-DIMETHYLBUTANEDIOIC ACID

Systematic Name

English

BUTANEDIOIC ACID, 2,2-DIMETHYL-

Common Name

English

SUCCINIC ACID, 2,2-DIMETHYL-

Common Name

English

Code System Code Type Description

CHEBI

86537