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Details

Stereochemistry ACHIRAL
Molecular Formula Ag.Cl
Molecular Weight 143.321
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SILVER CHLORIDE

SMILES

[Cl-].[Ag+]

InChI

InChIKey=HKZLPVFGJNLROG-UHFFFAOYSA-M
InChI=1S/Ag.ClH/h;1H/q+1;/p-1

HIDE SMILES / InChI

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Ag
Molecular Weight 107.8682
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including https://www.drugs.com/monograph/silver-nitrate.html | https://www.ncbi.nlm.nih.gov/pubmed/18245232

Silver iodide is an inorganic compound with the formula AgI. It is used as a photosensitive agent in photography, as a local antiseptic, as a chemical intermediate, and in cloud seeding for rain-making. The major hazards encountered in the use and handling of silver iodide stem from its toxicologic properties. Effects from exposure may include skin rashes, conjunctivitis, argyria (a permanent ashen-gray discoloration of skin, conjunctiva, and internal organs), headache, fever, hypersensitivity, laryngitis, and bronchitis.

Originator

Sources: Vestsi Akademii Navuk BSSR, Seryya Khimichnykh Navuk, Issue 2, Pages 69-73, Journal, 1990https://www.ncbi.nlm.nih.gov/pubmed/20429870
Curator's Comment: The medical uses of silver date back to at least the time of Hippocrates

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Advantage Arrest Silver Diamine Fluoride

Approved Use

Unknown
Primary
Advantage Arrest Silver Diamine Fluoride

Approved Use

Unknown
Primary
Unknown

Approved Use

Unknown
Curative
Unknown

Approved Use

Unknown
Curative
Unknown

Approved Use

Unknown
Primary
Colloidal silver iodide

Approved Use

Solution containing 5 to 49% of colloidal silver iodide have been employed in the treatment of infections of the mucous membranes. Ointments, usually containing 5%, have been used in inflammatory conditions of the eye, ear, and nose.
Primary
Colloidal silver iodide

Approved Use

Solution containing 5 to 49% of colloidal silver iodide have been employed in the treatment of infections of the mucous membranes. Ointments, usually containing 5%, have been used in inflammatory conditions of the eye, ear, and nose.
Palliative
Unknown

Approved Use

Antiseptic Wound Cauterization
Primary
Unknown

Approved Use

Prophylaxis of gonococcal ophthalmia neonatorum. AAP recommends use of topical silver nitrate, povidone-iodine, or possibly erythromycin for prophylaxis of nongonococcal nonchlamydial conjunctivitis in neonates, ideally administered shortly after birth.
PubMed

PubMed

TitleDatePubMed
Lack of genotoxicity of silver iodide in the SCE assay in vitro, in vivo, and in the Ames/microsome test.
1998
A chemically intelligent antimicrobial coating for urologic devices.
2000 Feb
Comparative efficacy of hand hygiene agents in the reduction of bacteria and viruses.
2005 Mar
Photocatalytic degradation of pathogenic bacteria with AgI/TiO2 under visible light irradiation.
2007 Apr 24
Topical antimicrobials for burn wound infections.
2010 Jun
Development of silica-coated silver iodide nanoparticles and their biodistribution.
2012 Dec
A novel silver iodide metalo-drug: experimental and computational modelling assessment of its interaction with intracellular DNA, lipoxygenase and glutathione.
2014 Apr 22
Patents

Sample Use Guides

In Vivo Use Guide
Curator's Comment: Toxicity data
Topical as a 1:80 dilution (30 ppm ionic silver).
Route of Administration: Topical
10 mkl volume of undiluted human norovirus 20% faecal suspension was mixed with 90 mkl of SDC (Silver Dihydrogen Citrate) for various contact times (15, 30, 60, 120, 300, 600 and 1800 s). At each sampling time point, 20 mkl of this solution was added to 180 mkl of 10% solution of Dey/Engley (D/E) neutralizing broth (Thermo Fisher Scientific, Waltham, MA). Samples were aliquoted and frozen at -80°C prior to nucleic acid extraction.
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:13:41 GMT 2023
Edited
by admin
on Fri Dec 15 16:13:41 GMT 2023
Record UNII
MWB0804EO7
Record Status Validated (UNII)
Record Version
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Name Type Language
SILVER CHLORIDE
INCI   MI   WHO-DD  
INCI  
Official Name English
SILVER CHLORIDE [MI]
Common Name English
SILVER(I) CHLORIDE
Systematic Name English
ARGENTUM MURIATICUM
HPUS  
Common Name English
SILVER CHLORIDE [INCI]
Common Name English
ARGENTUM MURIATICUM [HPUS]
Common Name English
Silver chloride [WHO-DD]
Common Name English
SILVER MONOCHLORIDE
Systematic Name English
Classification Tree Code System Code
CFR 21 CFR 310.548
Created by admin on Fri Dec 15 16:13:41 GMT 2023 , Edited by admin on Fri Dec 15 16:13:41 GMT 2023
EPA PESTICIDE CODE 72506
Created by admin on Fri Dec 15 16:13:41 GMT 2023 , Edited by admin on Fri Dec 15 16:13:41 GMT 2023
Code System Code Type Description
SMS_ID
100000078593
Created by admin on Fri Dec 15 16:13:41 GMT 2023 , Edited by admin on Fri Dec 15 16:13:41 GMT 2023
PRIMARY
FDA UNII
MWB0804EO7
Created by admin on Fri Dec 15 16:13:41 GMT 2023 , Edited by admin on Fri Dec 15 16:13:41 GMT 2023
PRIMARY
RXCUI
1314846
Created by admin on Fri Dec 15 16:13:41 GMT 2023 , Edited by admin on Fri Dec 15 16:13:41 GMT 2023
PRIMARY RxNorm
MERCK INDEX
m9918
Created by admin on Fri Dec 15 16:13:41 GMT 2023 , Edited by admin on Fri Dec 15 16:13:41 GMT 2023
PRIMARY Merck Index
CAS
7783-90-6
Created by admin on Fri Dec 15 16:13:41 GMT 2023 , Edited by admin on Fri Dec 15 16:13:41 GMT 2023
PRIMARY
CHEBI
30341
Created by admin on Fri Dec 15 16:13:41 GMT 2023 , Edited by admin on Fri Dec 15 16:13:41 GMT 2023
PRIMARY
MESH
C037548
Created by admin on Fri Dec 15 16:13:41 GMT 2023 , Edited by admin on Fri Dec 15 16:13:41 GMT 2023
PRIMARY
PUBCHEM
24561
Created by admin on Fri Dec 15 16:13:41 GMT 2023 , Edited by admin on Fri Dec 15 16:13:41 GMT 2023
PRIMARY
EVMPD
SUB15245MIG
Created by admin on Fri Dec 15 16:13:41 GMT 2023 , Edited by admin on Fri Dec 15 16:13:41 GMT 2023
PRIMARY
ECHA (EC/EINECS)
232-033-3
Created by admin on Fri Dec 15 16:13:41 GMT 2023 , Edited by admin on Fri Dec 15 16:13:41 GMT 2023
PRIMARY
EPA CompTox
DTXSID4035251
Created by admin on Fri Dec 15 16:13:41 GMT 2023 , Edited by admin on Fri Dec 15 16:13:41 GMT 2023
PRIMARY
DAILYMED
MWB0804EO7
Created by admin on Fri Dec 15 16:13:41 GMT 2023 , Edited by admin on Fri Dec 15 16:13:41 GMT 2023
PRIMARY
WIKIPEDIA
SILVER CHLORIDE
Created by admin on Fri Dec 15 16:13:41 GMT 2023 , Edited by admin on Fri Dec 15 16:13:41 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY