CRYPTOPINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H23NO5
Molecular Weight	369.411
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC2=C(C=C1OC)C(=O)CC3=CC=C4OCOC4=C3CN(C)CC2

InChI

InChIKey=XPOJSWHIKCNLEQ-UHFFFAOYSA-N

InChI=1S/C21H23NO5/c1-22-7-6-14-9-19(24-2)20(25-3)10-15(14)17(23)8-13-4-5-18-21(16(13)11-22)27-12-26-18/h4-5,9-10H,6-8,11-12H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C21H23NO5
Molecular Weight	369.411
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/15151168

Cryptopine is an opium alkaloid, which was found in the highest relative concentration in F. rostellata (25.1 %), F. schrammii (17.6 %) and F. thuretii (16.3 %). Experiments on animal have shown that cryptopine disturbs the cellular defense system.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
[On the companion alkaloids of morphine. 4. Identification and semi-quantitative determination of narcotoline, cryptopine, papaverine and narceine in the single phases of the Kabay procedure for preparation of morphine].	1968 Dec	5716918
Recovery of thebaine and cryptopine from Indian opium.	1980	6907026
Direct determination of alkaloid contents in Fumaria species by GC-MS.	2002 Nov-Dec	12494757
Stimulation of lipid peroxidation and impairment of glutathione-dependent defense system in Wistar rats treated with cryptopine, a rare non-narcotic opium alkaloid.	2004 Jan-Mar	15151168

Patents

Sample Use Guides

In Vivo Use Guide

disturbs the cellular defense system in rats: 50, 100, 150, 200 mg/kg bwt

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 04:29:04 GMT 2023` Edited by `admin` on `Sat Dec 16 04:29:04 GMT 2023`
Record UNII	MW13X5YK4A
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CRYPTOPINE

Common Name

English

4,6,7,13-TETRAHYDRO-9,10-DIMETHOXY-5-METHYLBENZO(G)-1,3-BENZODIOXOLO(4,5-C)AZECIN-12(5H)-ONE

Systematic Name

English

CRYPTOPINE [MI]

Common Name

English

CRYPTOPIN

Common Name

English

NSC-32984

Code

English

CRYPTOCAVINE

Common Name

English

KRYPTOPINE

Common Name

English

KRYPTOCAVIN

Common Name

English

Code System Code Type Description

ECHA (EC/EINECS)

207-584-8