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Details

Stereochemistry ACHIRAL
Molecular Formula C21H23NO5
Molecular Weight 369.411
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CRYPTOPINE

SMILES

COC1=CC2=C(C=C1OC)C(=O)CC3=CC=C4OCOC4=C3CN(C)CC2

InChI

InChIKey=XPOJSWHIKCNLEQ-UHFFFAOYSA-N
InChI=1S/C21H23NO5/c1-22-7-6-14-9-19(24-2)20(25-3)10-15(14)17(23)8-13-4-5-18-21(16(13)11-22)27-12-26-18/h4-5,9-10H,6-8,11-12H2,1-3H3

HIDE SMILES / InChI

Molecular Formula C21H23NO5
Molecular Weight 369.411
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Cryptopine is an opium alkaloid, which was found in the highest relative concentration in F. rostellata (25.1 %), F. schrammii (17.6 %) and F. thuretii (16.3 %). Experiments on animal have shown that cryptopine disturbs the cellular defense system.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
[On the companion alkaloids of morphine. 4. Identification and semi-quantitative determination of narcotoline, cryptopine, papaverine and narceine in the single phases of the Kabay procedure for preparation of morphine].
1968 Dec
Recovery of thebaine and cryptopine from Indian opium.
1980
Direct determination of alkaloid contents in Fumaria species by GC-MS.
2002 Nov-Dec
Stimulation of lipid peroxidation and impairment of glutathione-dependent defense system in Wistar rats treated with cryptopine, a rare non-narcotic opium alkaloid.
2004 Jan-Mar
Patents

Patents

Sample Use Guides

disturbs the cellular defense system in rats: 50, 100, 150, 200 mg/kg bwt
Route of Administration: Oral
In Vitro Use Guide
Curator's Comment: Protopine enhances 3H-gamma-aminobutyric acid (3H-GABA) binding to rat brain synaptic membrane receptors
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 16 04:29:04 GMT 2023
Edited
by admin
on Sat Dec 16 04:29:04 GMT 2023
Record UNII
MW13X5YK4A
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CRYPTOPINE
MI  
Common Name English
4,6,7,13-TETRAHYDRO-9,10-DIMETHOXY-5-METHYLBENZO(G)-1,3-BENZODIOXOLO(4,5-C)AZECIN-12(5H)-ONE
Systematic Name English
CRYPTOPINE [MI]
Common Name English
CRYPTOPIN
Common Name English
NSC-32984
Code English
CRYPTOCAVINE
Common Name English
KRYPTOPINE
Common Name English
KRYPTOCAVIN
Common Name English
Code System Code Type Description
ECHA (EC/EINECS)
207-584-8
Created by admin on Sat Dec 16 04:29:04 GMT 2023 , Edited by admin on Sat Dec 16 04:29:04 GMT 2023
PRIMARY
CAS
482-74-6
Created by admin on Sat Dec 16 04:29:04 GMT 2023 , Edited by admin on Sat Dec 16 04:29:04 GMT 2023
PRIMARY
FDA UNII
MW13X5YK4A
Created by admin on Sat Dec 16 04:29:04 GMT 2023 , Edited by admin on Sat Dec 16 04:29:04 GMT 2023
PRIMARY
PUBCHEM
72616
Created by admin on Sat Dec 16 04:29:04 GMT 2023 , Edited by admin on Sat Dec 16 04:29:04 GMT 2023
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MERCK INDEX
m3868
Created by admin on Sat Dec 16 04:29:04 GMT 2023 , Edited by admin on Sat Dec 16 04:29:04 GMT 2023
PRIMARY Merck Index
NSC
32984
Created by admin on Sat Dec 16 04:29:04 GMT 2023 , Edited by admin on Sat Dec 16 04:29:04 GMT 2023
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WIKIPEDIA
Cryptopine
Created by admin on Sat Dec 16 04:29:04 GMT 2023 , Edited by admin on Sat Dec 16 04:29:04 GMT 2023
PRIMARY
EPA CompTox
DTXSID40197463
Created by admin on Sat Dec 16 04:29:04 GMT 2023 , Edited by admin on Sat Dec 16 04:29:04 GMT 2023
PRIMARY