CRYPTOPINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H23NO5
Molecular Weight	369.411
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC2=C(C=C1OC)C(=O)CC3=C(CN(C)CC2)C4=C(OCO4)C=C3

InChI

InChIKey=XPOJSWHIKCNLEQ-UHFFFAOYSA-N

InChI=1S/C21H23NO5/c1-22-7-6-14-9-19(24-2)20(25-3)10-15(14)17(23)8-13-4-5-18-21(16(13)11-22)27-12-26-18/h4-5,9-10H,6-8,11-12H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C21H23NO5
Molecular Weight	369.411
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/15151168

Cryptopine is an opium alkaloid, which was found in the highest relative concentration in F. rostellata (25.1 %), F. schrammii (17.6 %) and F. thuretii (16.3 %). Experiments on animal have shown that cryptopine disturbs the cellular defense system.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2596

PubMed

Title	Date	PubMed
Stimulation of lipid peroxidation and impairment of glutathione-dependent defense system in Wistar rats treated with cryptopine, a rare non-narcotic opium alkaloid.	2004-05-21	15151168
Direct determination of alkaloid contents in Fumaria species by GC-MS.	2002-12-24	12494757
Recovery of thebaine and cryptopine from Indian opium.	1980	6907026
[On the companion alkaloids of morphine. 4. Identification and semi-quantitative determination of narcotoline, cryptopine, papaverine and narceine in the single phases of the Kabay procedure for preparation of morphine].	1968-12	5716918

Patents

Sample Use Guides

In Vivo Use Guide

disturbs the cellular defense system in rats: 50, 100, 150, 200 mg/kg bwt

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:22:16 GMT 2025` Edited by `admin` on `Mon Mar 31 21:22:16 GMT 2025`
Record UNII	MW13X5YK4A
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CRYPTOPINE

Common Name

English

NSC-32984

Preferred Name

English

4,6,7,13-TETRAHYDRO-9,10-DIMETHOXY-5-METHYLBENZO(G)-1,3-BENZODIOXOLO(4,5-C)AZECIN-12(5H)-ONE

Systematic Name

English

CRYPTOPINE [MI]

Common Name

English

CRYPTOPIN

Common Name

English

CRYPTOCAVINE

Common Name

English

KRYPTOPINE

Common Name

English

KRYPTOCAVIN

Common Name

English

Code System Code Type Description

ECHA (EC/EINECS)

207-584-8