Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C7H4Cl3NO3 |
| Molecular Weight | 256.471 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)COC1=NC(Cl)=C(Cl)C=C1Cl
InChI
InChIKey=REEQLXCGVXDJSQ-UHFFFAOYSA-N
InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13)
| Molecular Formula | C7H4Cl3NO3 |
| Molecular Weight | 256.471 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Triclopyr is a chloropyridinyl compound herbicide used against woody and herbaceous weeds. Most triclopyr is sold as a triethylamine salt (abbreviated TEA) or butoxyethyl ester (abbreviated BEE) derivative of the parent chemical, triclopyr acid. Triclopyr TEA was registered with the EPA in 1979 and triclopyr BEE was registered in 1980 (#EPA). Both chemicals are used for weed control in forests, pastures, and on other grasses including home lawns.Triclopyr is sold under names such as Access, Crossbow, ET, Garlon, Grazon, PathFinder, Redeem, Rely, Remedy, and Turflon. It is often mixed other herbicides like picloram or 2,4-D to target a greater range of plant pests Triclopyr controls target weeds by mimicking the
plant hormone auxin, causing uncontrolled plant
growth. Low concentrations of triclopyr can stimulate RNA, DNA, and protein synthesis
leading to uncontrolled cell division and growth, and, ultimately, vascular tissue destruction.
Conversely, high concentrations of triclopyr can inhibit cell division and growth.
Originator
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Toxicity of neurons treated with herbicides and neuroprotection by mitochondria-targeted antioxidant SS31. | 2011-01 |
|
| Severe systemic intoxication following triclopyr-TEA ingestion. | 2010-11 |
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| Photoprotection by plant extracts: a new ecological means to reduce pesticide photodegradation. | 2010-09-08 |
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| Intraspecific geographic variation of fragrances acquired by orchid bees in native and introduced populations. | 2010-08 |
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| The occurrence of glyphosate, atrazine, and other pesticides in vernal pools and adjacent streams in Washington, DC, Maryland, Iowa, and Wyoming, 2005-2006. | 2009-08 |
|
| A piezoelectric immunosensor for the determination of pesticide residues and metabolites in fruit juices. | 2009-05-15 |
|
| A biomarker validation study of prenatal chlorpyrifos exposure within an inner-city cohort during pregnancy. | 2009-04 |
|
| Photodegradation of bentazon, clopyralid, and triclopyr on model leaves: importance of a systematic evaluation of pesticide photostability on crops. | 2009-03-11 |
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| Impact of pesticides use in agriculture: their benefits and hazards. | 2009-03 |
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| Dissipation of four forest-use herbicides at high latitudes. | 2008-10 |
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| Assessment of potential aquatic herbicide impacts to California aquatic ecosystems. | 2008-10 |
|
| Multiple stressor effects of herbicide, pH, and food on wetland zooplankton and a larval amphibian. | 2008-09 |
|
| Comments on "Evaluation of estrogenic activities of aquatic herbicides and surfactants using a rainbow trout vitellogenin assay". | 2008-07 |
|
| Perturbation of organogenesis by the herbicide atrazine in the amphibian Xenopus laevis. | 2008-02 |
|
| Ten years of mixing cocktails: a review of combination effects of endocrine-disrupting chemicals. | 2007-12 |
|
| Determination of chlorinated acid herbicides in vegetation and soil by liquid chromatography/electrospray-tandem mass spectrometry. | 2007-10-25 |
|
| Efficacy of control measures for European buckthorn (Rhamnus cathartica L.) in Saskatchewan. | 2007-10 |
|
| Calibration of a passive sampling device for time-integrated sampling of hydrophilic herbicides in aquatic environments. | 2007-03 |
|
| Development and characterisation of an immunoaffinity chromatographic column for the on-line determination of the pesticide triclopyr. | 2007-02-28 |
|
| Optimisation of the separation of herbicides by linear gradient high performance liquid chromatography utilising artificial neural networks. | 2007-02-28 |
|
| Developmental toxicity evaluation of triclopyr butoxyethyl ester and triclopyr triethylamine salt in the CD rat. | 2007-02 |
|
| Acidic herbicides in surface waters of Lower Fraser Valley, British Columbia, Canada. | 2007-01-12 |
|
| Dacthal and chlorophenoxy herbicides and chlorothalonil fungicide in eggs of osprey (Pandion haliaetus) from the Duwamish-Lake Washington-Puget Sound area of Washington state, USA. | 2007-01 |
|
| Isotope dilution high-resolution gas chromatography/high-resolution mass spectrometry method for analysis of selected acidic herbicides in surface water. | 2006-11-10 |
|
| Heterogeneous photocatalysed degradation of two selected pesticide derivatives, triclopyr and daminozid in aqueous suspensions of titanium dioxide. | 2006-07 |
|
| Impact of data quality and model complexity on prediction of pesticide leaching. | 2006-03-03 |
|
| Evaluation of estrogenic activities of aquatic herbicides and surfactants using an rainbow trout vitellogenin assay. | 2005-10 |
|
| Worker exposures to triclopyr: risk assessment through measurements in urine samples. | 2005-07 |
|
| Tree thinning as an option to increase herbaceous yield of an encroached semi-arid savanna in South Africa. | 2005-05-28 |
|
| Determination of antagonism between cyhalofop-butyl and other rice (Oryza sativa) herbicides in barnyardgrass (Echinochloa crus-galli). | 2005-05-18 |
|
| Assessment of herbicide leaching risk in two tropical soils of Reunion Island (France). | 2005-03-11 |
|
| Physiological and biochemical characterization of quinclorac resistance in a false cleavers (Galium spurium L.) biotype. | 2005-02-23 |
|
| Carbaryl, 2,4-D, and Triclopyr adsorption in thatch-soil ecosystems. | 2005 |
|
| [Human health and pesticides used in the spraying of illicit crops: an issue of science or politics?]. | 2004-09-24 |
|
| Effect of pH and Release on two life stages of four anuran amphibians. | 2003-11 |
|
| Soil photolysis of herbicides in a moisture- and temperature-controlled environment. | 2003-07-16 |
|
| Turfgrass thatch effects on pesticide leaching: a laboratory and modeling study. | 2003-01-29 |
|
| Toxicokinetics, recovery, and metabolism of triclopyr butotyl (ACTP) ester in goats. | 2002-07-17 |
|
| Dissipation of triclopyr herbicide applied in Lake Minnetonka, MN concurrently with Rhodamine WT dye. | 2002-07 |
|
| New approach to immunochemical determinations for triclopyr and 3,5,6-trichloro-2-pyridinol by using a bifunctional hapten, and evaluation of polyclonal antiserum. | 2002-06-19 |
|
| Environmental fate of triclopyr. | 2002 |
|
| A test system to evaluate the susceptibility of Oregon, USA, native stream invertebrataes to triclopyr and carbaryl. | 2001-10 |
|
| The aquatic fate of triclopyr in whole-pond treatments. | 2001-09 |
|
| Assessing the potential for pesticide leaching for the pine forest areas of Tenerife. | 2001-09 |
Sample Use Guides
The oral LD50 of triclopyr in rats ranges from 630 to 729 mg/kg. Rats fed diets containing between 3 and 30 mg/kg/day of triclopyr experienced no ill effects. Males fed much higher doses (100 mg/kg) had decreased liver and body weight and increased kidney weight. The male mice were also sensitive at moderate doses. They had reduced liver weight at 60 mg/kg/day. Monkeys fed small amounts of triclopyr (30 mg/kg/day) had no adverse effects.
Route of Administration:
Oral
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:31:26 GMT 2025
by
admin
on
Mon Mar 31 19:31:26 GMT 2025
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| Record UNII |
MV06PHJ6I0
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| Record Status |
Validated (UNII)
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| Record Version |
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EPA PESTICIDE CODE |
116001
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| Code System | Code | Type | Description | ||
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TRICLOPYR
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41428
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triclopyr
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m11091
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MV06PHJ6I0
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DTXSID0032497
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C032742
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