COUMESTAN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C15H8O3
Molecular Weight	236.2222
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O=C1OC2=CC=CC=C2C3=C1C4=CC=CC=C4O3

InChI

InChIKey=JBIZUYWOIKFETJ-UHFFFAOYSA-N

InChI=1S/C15H8O3/c16-15-13-9-5-1-3-7-11(9)17-14(13)10-6-2-4-8-12(10)18-15/h1-8H

HIDE SMILES / InChI

Molecular Formula	C15H8O3
Molecular Weight	236.2222
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
[Studies on the chemical constituents of Eclipta prostrata (L)].	2001 Jan	12579857
Cytotoxic constituents of Psoralea corylifolia.	2001 Jun	11440079
Flavonoids from Glycyrrhiza pallidiflora hairy root cultures.	2001 Oct	11576605
A new coumestan from Tephrosia calophylla.	2003 Feb	12576655
Phyto-oestrogens and breast cancer chemoprevention.	2004	15084232
Furanoflavonoids from Pongamia pinnata fruits.	2004 Feb	14759538
Characterization of a new synthetic isoflavonoid with inverse agonist activity at the central benzodiazepine receptor.	2004 Jul 14	15249156
Identification and concentration of soy phytoestrogens in commercial dog foods.	2004 May	15141878
New cytotoxic prenylated isoflavonoids from Bituminaria morisiana.	2005 Mar	15770547
Expression profiling of the estrogen responsive genes in response to phytoestrogens using a customized DNA microarray.	2005 Mar 14	15757668
Phytoestrogen content of foods consumed in Canada, including isoflavones, lignans, and coumestan.	2006	16898863
Coumestans from Hedysarum multijugum.	2006 Jun	16792403
Phytoestrogens as inhibitors of the human progesterone metabolizing enzyme AKR1C1.	2006 Oct 19	16962702
Intake of dietary phytoestrogen and indices of antioxidant and bone metabolism of pre- and post-menopausal Korean women.	2007 Winter	20368955
Antioxidant 2-phenylbenzofurans and a coumestan from Lespedeza virgata.	2008 Jun	18484774
Insights into the mechanism of Na+,K+-ATPase inhibition by 2-methoxy-3,8,9-trihydroxy coumestan.	2008 Oct 1	18805699
Comparative study on the nuclear hormone receptor activity of various phytochemicals and their metabolites by reporter gene assays using Chinese hamster ovary cells.	2009 Feb	19182375
Cytotoxic benzil and coumestan derivatives from Tephrosia calophylla.	2009 Jan	19062050
Honeybush (Cyclopia sp.) - a rich source of compounds with high antimutagenic properties.	2009 Jan	19032980
Coumestan glycosides from the stem bark of Cylicodiscus gabunensis.	2009 Jul	19731596
Combined directed ortho and remote metalation-Suzuki cross-coupling strategies. Efficient synthesis of heteroaryl-fused benzopyranones from biaryl O-carbamates.	2009 Jun 5	19441801
Development of an alcohol dehydrogenase biosensor for ethanol determination with toluidine blue O covalently attached to a cellulose acetate modified electrode.	2010	22315566
AMP-activated protein kinase (AMPK) activation by benzofurans and coumestans isolated from Erythrina abyssinica.	2010 Apr 23	20337486
Inhibition of neuraminidase activity by polyphenol compounds isolated from the roots of Glycyrrhiza uralensis.	2010 Feb 1	20064716
Ability of a synthetic coumestan to antagonize Bothrops snake venom activities.	2010 Feb-Mar	19883675
Psoralea corylifolia Linn.-"Kushtanashini".	2010 Jan	22228944
Antioxidant activity of tuberosin isolated from Pueraria tuberose Linn.	2010 Sep 14	20836891

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:44:43 UTC 2023` Edited by `admin` on `Fri Dec 15 19:44:43 UTC 2023`
Record UNII	MT103Z562V
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

COUMESTAN

Common Name

English

(1)BENZOXOLO(3,2-C)CHROMEN-6-ONE

Systematic Name

English

Code System Code Type Description

WIKIPEDIA

COUMESTAN