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Details

Stereochemistry ACHIRAL
Molecular Formula C15H8O3
Molecular Weight 236.2222
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of COUMESTAN

SMILES

O=C1OC2=C(C=CC=C2)C3=C1C4=C(O3)C=CC=C4

InChI

InChIKey=JBIZUYWOIKFETJ-UHFFFAOYSA-N
InChI=1S/C15H8O3/c16-15-13-9-5-1-3-7-11(9)17-14(13)10-6-2-4-8-12(10)18-15/h1-8H

HIDE SMILES / InChI

Molecular Formula C15H8O3
Molecular Weight 236.2222
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Antioxidant activity of tuberosin isolated from Pueraria tuberose Linn.
2010-09-14
AMP-activated protein kinase (AMPK) activation by benzofurans and coumestans isolated from Erythrina abyssinica.
2010-04-23
Inhibition of neuraminidase activity by polyphenol compounds isolated from the roots of Glycyrrhiza uralensis.
2010-02-01
Psoralea corylifolia Linn.-"Kushtanashini".
2010-01
Development of an alcohol dehydrogenase biosensor for ethanol determination with toluidine blue O covalently attached to a cellulose acetate modified electrode.
2010
Ability of a synthetic coumestan to antagonize Bothrops snake venom activities.
2009-07-22
Coumestan glycosides from the stem bark of Cylicodiscus gabunensis.
2009-07
Combined directed ortho and remote metalation-Suzuki cross-coupling strategies. Efficient synthesis of heteroaryl-fused benzopyranones from biaryl O-carbamates.
2009-06-05
Comparative study on the nuclear hormone receptor activity of various phytochemicals and their metabolites by reporter gene assays using Chinese hamster ovary cells.
2009-02
Cytotoxic benzil and coumestan derivatives from Tephrosia calophylla.
2009-01
Honeybush (Cyclopia sp.) - a rich source of compounds with high antimutagenic properties.
2009-01
Insights into the mechanism of Na+,K+-ATPase inhibition by 2-methoxy-3,8,9-trihydroxy coumestan.
2008-10-01
Antioxidant 2-phenylbenzofurans and a coumestan from Lespedeza virgata.
2008-06
Intake of dietary phytoestrogen and indices of antioxidant and bone metabolism of pre- and post-menopausal Korean women.
2007
Structure-activity relationship of wedelolactone analogues: structural requirements for inhibition of Na+, K+ -ATPase and binding to the central benzodiazepine receptor.
2006-12-01
Phytoestrogens as inhibitors of the human progesterone metabolizing enzyme AKR1C1.
2006-10-19
Coumestans from Hedysarum multijugum.
2006-06
Phytoestrogen content of foods consumed in Canada, including isoflavones, lignans, and coumestan.
2006
An efficient synthesis of coumestrol and coumestans by iodocyclization and Pd-catalyzed intramolecular lactonization.
2005-11-25
Computational electrode potential of a coumestan derivative: theoretical and experimental studies.
2005-08-22
Expression profiling of the estrogen responsive genes in response to phytoestrogens using a customized DNA microarray.
2005-03-14
New cytotoxic prenylated isoflavonoids from Bituminaria morisiana.
2005-03
Characterization of a new synthetic isoflavonoid with inverse agonist activity at the central benzodiazepine receptor.
2004-07-14
Identification and concentration of soy phytoestrogens in commercial dog foods.
2004-05
Furanoflavonoids from Pongamia pinnata fruits.
2004-02
Regulation of low-density lipoprotein receptor activity by estrogens and phytoestrogens in a HepG2 cell model.
2004
Phyto-oestrogens and breast cancer chemoprevention.
2004
A new coumestan from Tephrosia calophylla.
2003-02
Flavonoids from Glycyrrhiza pallidiflora hairy root cultures.
2001-10
Cytotoxic constituents of Psoralea corylifolia.
2001-06
[Studies on the chemical constituents of Eclipta prostrata (L)].
2001-01
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:55:45 GMT 2025
Edited
by admin
on Mon Mar 31 19:55:45 GMT 2025
Record UNII
MT103Z562V
Record Status Validated (UNII)
Record Version
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Name Type Language
(1)BENZOXOLO(3,2-C)CHROMEN-6-ONE
Preferred Name English
COUMESTAN
Common Name English
Code System Code Type Description
WIKIPEDIA
COUMESTAN
Created by admin on Mon Mar 31 19:55:45 GMT 2025 , Edited by admin on Mon Mar 31 19:55:45 GMT 2025
PRIMARY
EPA CompTox
DTXSID30197316
Created by admin on Mon Mar 31 19:55:45 GMT 2025 , Edited by admin on Mon Mar 31 19:55:45 GMT 2025
PRIMARY
PUBCHEM
638309
Created by admin on Mon Mar 31 19:55:45 GMT 2025 , Edited by admin on Mon Mar 31 19:55:45 GMT 2025
PRIMARY
CAS
479-12-9
Created by admin on Mon Mar 31 19:55:45 GMT 2025 , Edited by admin on Mon Mar 31 19:55:45 GMT 2025
PRIMARY
FDA UNII
MT103Z562V
Created by admin on Mon Mar 31 19:55:45 GMT 2025 , Edited by admin on Mon Mar 31 19:55:45 GMT 2025
PRIMARY