SCRIPTENE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H24N9O9P
Molecular Weight	565.4332
Optical Activity	UNSPECIFIED
Defined Stereocenters	5 / 5
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](COP(O)(=O)OC[C@@H]3CC[C@@H](O3)N4C=NC5=C4N=CNC5=O)O2)C(=O)NC1=O

InChI

InChIKey=XURFYCWNUGWGDL-VQJWOFKYSA-N

InChI=1S/C20H24N9O9P/c1-10-5-28(20(32)25-18(10)30)15-4-12(26-27-21)13(38-15)7-36-39(33,34)35-6-11-2-3-14(37-11)29-9-24-16-17(29)22-8-23-19(16)31/h5,8-9,11-15H,2-4,6-7H2,1H3,(H,33,34)(H,22,23,31)(H,25,30,32)/t11-,12-,13+,14+,15+/m0/s1

HIDE SMILES / InChI

Molecular Formula	C20H24N9O9P
Molecular Weight	565.4332
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	5 / 5
E/Z Centers	1
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Synthesis, antiviral activity, cytotoxicity and cellular pharmacology of l-3'-azido-2',3'-dideoxypurine nucleosides.	2011-09	21700368
Generation of drug-resistant variants of human immunodeficiency virus type 1 by in vitro passage in increasing concentrations of 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidine.	1993-01	8381634
Activities of 3'-azido-3'-deoxythymidine nucleotide dimers in primary lymphocytes infected with human immunodeficiency virus type 1.	1990-06	2393266
Nucleotide dimers suppress HIV expression in vitro.	1988-12	2464362

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:47:17 GMT 2025` Edited by `admin` on `Mon Mar 31 18:47:17 GMT 2025`
Record UNII	MRB2FUC61I
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SCRIPTENE

Preferred Name

English

Code System Code Type Description

MESH

C106062