Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C12H14N3O7.Na.2H2O |
| Molecular Weight | 371.2758 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 1 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O.O.[Na+].O[C@@H](\C=N\NC(=O)C1=CC=NC=C1)[C@@H](O)[C@H](O)[C@H](O)C([O-])=O
InChI
InChIKey=ACIFZFQSDOHAIU-KMDBVMTBSA-M
InChI=1S/C12H15N3O7.Na.2H2O/c16-7(8(17)9(18)10(19)12(21)22)5-14-15-11(20)6-1-3-13-4-2-6;;;/h1-5,7-10,16-19H,(H,15,20)(H,21,22);;2*1H2/q;+1;;/p-1/b14-5+;;;/t7-,8+,9-,10-;;;/m0.../s1
| Molecular Formula | Na |
| Molecular Weight | 22.9898 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C12H14N3O7 |
| Molecular Weight | 312.2555 |
| Charge | -1 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 1 |
| Optical Activity | UNSPECIFIED |
| Molecular Formula | H2O |
| Molecular Weight | 18.0153 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Isoniazid glucuronate is a less toxic derivative the antibacterial drug isoniazid. Isoniazid is recommended for all forms of tuberculosis in which organisms are susceptible. Isoniazid itself is a prodrug and must be activated by bacterial catalase. Isoniazid inhibits InhA, the enoyl reductase from Mycobacterium tuberculosis, by forming a covalent adduct with the NAD cofactor.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 07:49:11 GMT 2023
by
admin
on
Sat Dec 16 07:49:11 GMT 2023
|
| Record UNII |
MR1AAS6141
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
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| Code System | Code | Type | Description | ||
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CHEMBL2110846
Created by
admin on Sat Dec 16 07:49:12 GMT 2023 , Edited by admin on Sat Dec 16 07:49:12 GMT 2023
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PRIMARY | |||
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53297476
Created by
admin on Sat Dec 16 07:49:12 GMT 2023 , Edited by admin on Sat Dec 16 07:49:12 GMT 2023
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PRIMARY | |||
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MR1AAS6141
Created by
admin on Sat Dec 16 07:49:12 GMT 2023 , Edited by admin on Sat Dec 16 07:49:12 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
ANHYDROUS->SOLVATE |
