Approval Year
| Substance Class |
Structurally Diverse
Created
by
admin
on
Edited
Wed Apr 02 12:40:18 GMT 2025
by
admin
on
Wed Apr 02 12:40:18 GMT 2025
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| Source Materials Class | ORGANISM |
| Source Materials Type | VIRUS |
| Source Materials State | LIVE ATTENUATED GENETICALLY MODIFIED |
| Organism Family | Picornaviridae |
| Organism Genus | Enterovirus |
| Organism Species | human enterovirus c |
| Infraspecific Type | RECOMBINANT VECTOR |
| Infraspecific Name | PVSRIPO |
| Part | whole |
| Record UNII |
MQ5GV2WUK4
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| Record Status |
Validated (UNII)
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| Record Version |
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-
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Preferred Name | English | ||
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Official Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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2430048-02-3
Created by
admin on Wed Apr 02 12:40:18 GMT 2025 , Edited by admin on Wed Apr 02 12:40:18 GMT 2025
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PRIMARY | |||
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C184921
Created by
admin on Wed Apr 02 12:40:18 GMT 2025 , Edited by admin on Wed Apr 02 12:40:18 GMT 2025
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PRIMARY | |||
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300000041916
Created by
admin on Wed Apr 02 12:40:18 GMT 2025 , Edited by admin on Wed Apr 02 12:40:18 GMT 2025
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PRIMARY | |||
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11897
Created by
admin on Wed Apr 02 12:40:18 GMT 2025 , Edited by admin on Wed Apr 02 12:40:18 GMT 2025
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PRIMARY | |||
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MQ5GV2WUK4
Created by
admin on Wed Apr 02 12:40:18 GMT 2025 , Edited by admin on Wed Apr 02 12:40:18 GMT 2025
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
TARGET -> INHIBITOR |
PVS-RIPO is administered intratumorally via catheter and can infect and lyse any cell expressing the CD155 molecule
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
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Structural Modifications
| Modification Type | Location Site | Location Type | Residue Modified | Extent | Fragment Name | Fragment Approval |
|---|---|---|---|---|---|---|
| CHIMERIC GENOME | LERAPOLTUREV CHIMERIC GENOME | ETC97PP2WB |