Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C22H24Cl2N4O3 |
| Molecular Weight | 463.357 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NCCNC1=CC=C(OC[C@H]2CO[C@@](CN3C=CN=C3)(O2)C4=C(Cl)C=C(Cl)C=C4)C=C1
InChI
InChIKey=URTUWKMGVFPWPN-UGKGYDQZSA-N
InChI=1S/C22H24Cl2N4O3/c23-16-1-6-20(21(24)11-16)22(14-28-10-9-26-15-28)30-13-19(31-22)12-29-18-4-2-17(3-5-18)27-8-7-25/h1-6,9-11,15,19,27H,7-8,12-14,25H2/t19-,22-/m0/s1
| Molecular Formula | C22H24Cl2N4O3 |
| Molecular Weight | 463.357 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Tue Apr 01 21:17:32 GMT 2025
by
admin
on
Tue Apr 01 21:17:32 GMT 2025
|
| Record UNII |
MQ22FM3GHH
|
| Record Status |
Validated (UNII)
|
| Record Version |
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-
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Common Name | English | ||
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Preferred Name | English |
| Code System | Code | Type | Description | ||
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MQ22FM3GHH
Created by
admin on Tue Apr 01 21:17:32 GMT 2025 , Edited by admin on Tue Apr 01 21:17:32 GMT 2025
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101672308
Created by
admin on Tue Apr 01 21:17:32 GMT 2025 , Edited by admin on Tue Apr 01 21:17:32 GMT 2025
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159898-60-9
Created by
admin on Tue Apr 01 21:17:32 GMT 2025 , Edited by admin on Tue Apr 01 21:17:32 GMT 2025
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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PARENT -> METABOLITE INACTIVE |
Evidence that CYP3A4 plays a significant role in metabolism of ketoconazole is that co-administration of CYP3A4 inducers, such as phenytoin, carbamazepine, and rifampin, can cause as much as a 50% reduction in levels of ketoconazole.
MAY BE CLINICALLY SIGNIFICANT
|
