INDANIDINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C11H13N5
Molecular Weight	215.2544
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN1C=C2C(C=CC=C2NC3=NCCN3)=N1

InChI

InChIKey=PNHJTLDBYZVCGW-UHFFFAOYSA-N

InChI=1S/C11H13N5/c1-16-7-8-9(3-2-4-10(8)15-16)14-11-12-5-6-13-11/h2-4,7H,5-6H2,1H3,(H2,12,13,14)

HIDE SMILES / InChI

Molecular Formula	C11H13N5
Molecular Weight	215.2544
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/12591110 | http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=4526898.PN.&OS=PN/4526898&RS=PN/4526898 | https://www.ncbi.nlm.nih.gov/pubmed/1686324

Indanidine is a selective and effective α2-antagonist, α1-partial agonist patented by pharmaceutical company Siegfried A.-G as a low toxic compound with direct hypotensive action. Indanidine does not penetrate the blood-brain barrier, does not induce drug-metabolizing enzymes in the liver, does not cause behavioral changes.

CNS Activity

Originator

Approval Year

PubMed

Title	Date	PubMed
Selectivity of agonists for cloned alpha 1-adrenergic receptor subtypes.	1994 Nov	7969082

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:27:22 GMT 2023` Edited by `admin` on `Fri Dec 15 16:27:22 GMT 2023`
Record UNII	MP564IFE34
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

INDANIDINE

Official Name

English

Indanidine [WHO-DD]

Common Name

English

4-(2-IMIDAZOLIN-2-YLAMINO)-2-METHYL-2H-INDAZOLE

Systematic Name

English

indanidine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29709