Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C27H46O |
| Molecular Weight | 386.6535 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 8 / 8 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
InChI
InChIKey=HVYWMOMLDIMFJA-VEIPTCAHSA-N
InChI=1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21-,22+,23-,24+,25+,26+,27-/m1/s1
| Molecular Formula | C27H46O |
| Molecular Weight | 386.6535 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 8 / 8 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Preoperative lipid control with simvastatin reduces the risk for graft failure already 1 year after myocardial revascularization. | 2001-02 |
|
| Glycated haemoglobin, diabetes, and mortality in men in Norfolk cohort of european prospective investigation of cancer and nutrition (EPIC-Norfolk). | 2001-01-06 |
|
| Cholesterol reduction and non-illness mortality: meta-analysis of randomised clinical trials. | 2001-01-06 |
|
| Cardiovascular effects of tamoxifen in women with and without heart disease: breast cancer prevention trial. National Surgical Adjuvant Breast and Bowel Project Breast Cancer Prevention Trial Investigators. | 2001-01-03 |
|
| Estrogen, selective estrogen receptor modulation, and coronary heart disease: something or nothing. | 2001-01-03 |
|
| Hydroxy-methylglutaryl-coenzyme A reductase inhibition promotes endothelial nitric oxide synthase activation through a decrease in caveolin abundance. | 2001-01-02 |
|
| Effect of type 2 diabetes mellitus on left ventricular geometry and systolic function in hypertensive subjects: Hypertension Genetic Epidemiology Network (HyperGEN) study. | 2001-01-02 |
|
| Women's Healthy Lifestyle Project: A randomized clinical trial: results at 54 months. | 2001-01-02 |
|
| Cracking down on caveolin: role of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in modulating edothelial cell nitric oxide production. | 2001-01-02 |
|
| Quantification of plasma membrane ergosterol of Saccharomyces cerevisiae by direct-injection atmospheric pressure chemical ionization/tandem mass spectrometry. | 2001-01-01 |
|
| High-density lipoprotein cholesterol and vascular stiffness at baseline in the activity counseling trial. | 2001-01-01 |
|
| Acute increases in plasma oxidized low-density lipoprotein immediately after percutaneous transluminal coronary angioplasty. | 2001-01-01 |
|
| Effects of atorvastatin versus fenofibrate on lipoprotein profiles, low-density lipoprotein subfraction distribution, and hemorheologic parameters in type 2 diabetes mellitus with mixed hyperlipoproteinemia. | 2001-01-01 |
|
| Pharmacological profile of F 12511, (S)-2',3', 5'-trimethyl-4'-hydroxy-alpha-dodecylthioacetanilide a powerful and systemic acylcoenzyme A: cholesterol acyltransferase inhibitor. | 2001-01-01 |
|
| Amyloid-beta is an antioxidant for lipoproteins in cerebrospinal fluid and plasma. | 2001-01-01 |
|
| Remodeling of the vessel wall after copper-induced injury is highly attenuated in mice with a total deficiency of plasminogen activator inhibitor-1. | 2001-01 |
|
| Life-style factors and risk for abdominal aortic aneurysm in a cohort of Finnish male smokers. | 2001-01 |
|
| Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption. | 2001-01 |
|
| Screening family members at high risk for coronary disease. Why isn't it done? | 2001-01 |
|
| Frequency of the R3500Q mutation of the apolipoprotein B-100 gene in a sample screened clinically for familial hypercholesterolemia in Hungary. | 2001-01 |
|
| Remnant-like particle (RLP) cholesterol is an independent cardiovascular disease risk factor in women: results from the Framingham Heart Study. | 2001-01 |
|
| Plasma lipids and cardiovascular risk: a POSCH report. Program on the Surgical Control of the Hyperlipidemias. | 2001-01 |
|
| The effect of a garlic preparation on plasma lipid levels in moderately hypercholesterolemic adults. | 2001-01 |
|
| Elevated plasma levels of free-form of TFPI antigen in hypercholesterolemic patients. | 2001-01 |
|
| Impaired renal vascular endothelial function in vitro in experimental hypercholesterolemia. | 2001-01 |
|
| Essential role for the (hepatic) LDL receptor in macrophage apolipoprotein E-induced reduction in serum cholesterol levels and atherosclerosis. | 2001-01 |
|
| Raloxifene and estrogen reduces progression of advanced atherosclerosis--a study in ovariectomized, cholesterol-fed rabbits. | 2001-01 |
|
| Anti-oxidative properties of fluvastatin, an HMG-CoA reductase inhibitor, contribute to prevention of atherosclerosis in cholesterol-fed rabbits. | 2001-01 |
|
| Gelatin intake increases the atheroma formation in apoE knock out mice. | 2001-01 |
|
| The LDL receptor is the major pathway for beta-VLDL uptake by mouse peritoneal macrophages. | 2001-01 |
|
| 17beta-estradiol, gender independently, reduces atheroma development but not neointimal proliferation after balloon injury in the rabbit aorta. | 2001-01 |
|
| Inability of plasma high-density lipoproteins to inhibit cell adhesion molecule expression in human coronary artery endothelial cells. | 2001-01 |
|
| The sialylation of plasma lipoproteins. | 2001-01 |
|
| Alcohol intake, type of beverage, and the risk of cerebral infarction in young women. | 2001-01 |
|
| Ask the doctor. I've been fighting obesity all my life. I'm a 62-year-old woman and every five years or so I lose about 20 pounds, then slowly gain it back. I've heard that this "yo-yo" pattern of weight loss, weight gain, weight loss, may be more dangerous than just staying heavy. Should I give up trying to lose weight? | 2001-01 |
|
| Ursodeoxycholic acid alone or with chenodeoxycholic acid for dissolution of cholesterol gallstones: a randomized multicentre trial. The British-Italian Gallstone Study group. | 2001-01 |
|
| PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway. | 2001-01 |
|
| The role of PPAR-gamma in macrophage differentiation and cholesterol uptake. | 2001-01 |
|
| Resolution of alcohols by cholesterol oxidase fromRrhodococcus erythropolis: lack of enantiospecificity for the steroids. | 2001-01 |
|
| Effect of lipid reduction on the progression of renal disease: a meta-analysis. | 2001-01 |
|
| Accumulation of cholesterol with age in human Bruch's membrane. | 2001-01 |
|
| Magnetic resonance imaging and spectroscopic changes in brains of patients with cerebrotendinous xanthomatosis. | 2001-01 |
|
| Role of meiosis-activating sterols in rat oocyte maturation: effects of specific inhibitors and changes in the expression of lanosterol 14alpha-demethylase during the preovulatory period. | 2001-01 |
|
| Dexamethasone inhibits luteinizing hormone-induced synthesis of steroidogenic acute regulatory protein in cultured rat preovulatory follicles. | 2001-01 |
|
| Meiosis-activating sterol and the maturation of isolated mouse oocytes. | 2001-01 |
|
| Body mass index and metabolic risk factors for coronary heart disease in women. | 2001-01 |
|
| Maternal hypercholesterolemia during pregnancy influences the later development of atherosclerosis: clinical and pathogenic implications. | 2001-01 |
|
| The effect of isolated soy protein on plasma biomarkers in elderly men with elevated serum prostate specific antigen. | 2001-01 |
|
| Oligonucleotides as inhibitors of protein synthesis. | 2001 |
|
| Eight novel LDL receptor gene mutations among patients under LDL apheresis in Dresden and Leipzig. | 2001 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:47:41 GMT 2025
by
admin
on
Mon Mar 31 21:47:41 GMT 2025
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| Record UNII |
MP3S3KD84I
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| Record Status |
Validated (UNII)
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| Record Version |
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5283629
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m4938
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474-77-1
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DTXSID50415281
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MP3S3KD84I
Created by
admin on Mon Mar 31 21:47:41 GMT 2025 , Edited by admin on Mon Mar 31 21:47:41 GMT 2025
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