MYFADOL

Details

Stereochemistry	MIXED
Molecular Formula	C21H25NO2
Molecular Weight	323.4287
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1N(CC(=O)C2=CC=CC=C2)CCCC1(C)C3=CC(O)=CC=C3

InChI

InChIKey=XMSWGYQEWPUOKA-UHFFFAOYSA-N

InChI=1S/C21H25NO2/c1-16-21(2,18-10-6-11-19(23)14-18)12-7-13-22(16)15-20(24)17-8-4-3-5-9-17/h3-6,8-11,14,16,23H,7,12-13,15H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C21H25NO2
Molecular Weight	323.4287
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5534689 | https://www.ncbi.nlm.nih.gov/pubmed/4148341 | https://www.ncbi.nlm.nih.gov/pubmed/5304859

Myfadol is a phenacylpiperidine derivative patented by Tanabe Seiyaku Co., Ltd as low molecular weight non-peptide analgesic. Myfadol produces hot-plate analgesia in rodents with minimal side-effects, and when given parenterally in humans produces analgesia to experimentally-produced and postoperative pain.

Originator

Approval Year

PubMed

Title	Date	PubMed
Pharmacological studies of 1-phenacyl-2,3-dimethyl-3-(3-hydroxyphenyl) piperidine hydrochloride (TA-306), an analgesic and antitussive agent.	1968 Dec	5304859

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:26:23 GMT 2023` Edited by `admin` on `Sat Dec 16 16:26:23 GMT 2023`
Record UNII	MON17C96OK
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MYFADOL

Official Name

English

ACETOPHENONE, 2-(3-(M-HYDROXYPHENYL)-2,3-DIMETHYLPIPERIDINO)-

Systematic Name

English

myfadol [INN]

Common Name

English

ETHANONE, 2-(3-(3-HYDROXYPHENYL)-2,3-DIMETHYL-1-PIPERIDINYL)-1-PHENYL-

Systematic Name

English

2-(3-(M-HYDROXYPHENYL)-2,3-DIMETHYLPIPERIDINO)ACETOPHENONE

Systematic Name

English

Code System Code Type Description

EVMPD

SUB09099MIG