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Details

Stereochemistry ABSOLUTE
Molecular Formula C22H31NO3.ClH
Molecular Weight 393.947
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LEVOPHENCYNONATE HYDROCHLORIDE

SMILES

Cl.CN1C[C@@H]2CCC[C@H](C1)[C@@H]2OC(=O)[C@@](O)(C3CCCC3)C4=CC=CC=C4

InChI

InChIKey=AUKYHFFECJXLHI-CTKRSBQWSA-N
InChI=1S/C22H31NO3.ClH/c1-23-14-16-8-7-9-17(15-23)20(16)26-21(24)22(25,19-12-5-6-13-19)18-10-3-2-4-11-18;/h2-4,10-11,16-17,19-20,25H,5-9,12-15H2,1H3;1H/t16?,17?,20?,22-;/m0./s1

HIDE SMILES / InChI

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C22H31NO3
Molecular Weight 357.4864
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Levophencynonate is the active enantiomer of phencynonate. Levophencynonate is an anticholinergic agent which can prevent acute motion sickness with an efficacy similar to scopolamine. It will take effect by competitive binding to central muscarinic acetylcholine receptors. In April 2017 levophencynonate was in preregistration phase for the vertigo treatment in China.

Approval Year

PubMed

PubMed

TitleDatePubMed
Simultaneous determination of levophencynonate and its metabolite demethyl levophencynonate in human plasma by liquid chromatography tandem mass spectrometry.
2016 Aug 1
Substance Class Chemical
Created
by admin
on Sat Dec 16 11:18:19 GMT 2023
Edited
by admin
on Sat Dec 16 11:18:19 GMT 2023
Record UNII
MOI46704GT
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LEVOPHENCYNONATE HYDROCHLORIDE
Common Name English
LEVO-PHENCYNONATE HYDROCHLORIDE
Common Name English
BENZENEACETIC ACID, .ALPHA.-CYCLOPENTYL-.ALPHA.-HYDROXY-, (9-ANTI)-3-METHYL-3-AZABICYCLO(3.3.1)NON-9-YL ESTER, HYDROCHLORIDE, (.ALPHA.R)-
Systematic Name English
R-(-)-PHENCYNONATE HYDROCHLORIDE
Common Name English
Levophencynonate hydrochloride [WHO-DD]
Common Name English
Code System Code Type Description
CAS
861655-73-4
Created by admin on Sat Dec 16 11:18:19 GMT 2023 , Edited by admin on Sat Dec 16 11:18:19 GMT 2023
PRIMARY
PUBCHEM
70675843
Created by admin on Sat Dec 16 11:18:19 GMT 2023 , Edited by admin on Sat Dec 16 11:18:19 GMT 2023
PRIMARY
FDA UNII
MOI46704GT
Created by admin on Sat Dec 16 11:18:19 GMT 2023 , Edited by admin on Sat Dec 16 11:18:19 GMT 2023
PRIMARY
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ACTIVE MOIETY