Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H4Cl6 |
| Molecular Weight | 360.878 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
ClC1=CC=C(Cl)C(=C1Cl)C2=C(Cl)C(Cl)=CC=C2Cl
InChI
InChIKey=FZFUUSROAHKTTF-UHFFFAOYSA-N
InChI=1S/C12H4Cl6/c13-5-1-3-7(15)11(17)9(5)10-6(14)2-4-8(16)12(10)18/h1-4H
| Molecular Formula | C12H4Cl6 |
| Molecular Weight | 360.878 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| 2,2',3,3',6,6'-Hexachlorobiphenyl (PCB 136) is enantioselectively oxidized to hydroxylated metabolites by rat liver microsomes. | 2011-12-19 |
|
| In vitro toxicity profiling of ultrapure non-dioxin-like polychlorinated biphenyl congeners and their relative toxic contribution to PCB mixtures in humans. | 2011-05 |
|
| Non-dioxin-like-PCBs phosphorylate Mdm2 at Ser166 and attenuate the p53 response in HepG2 cells. | 2009-12-10 |
|
| Enantiomeric specificity of (-)-2,2',3,3',6,6'-hexachlorobiphenyl toward ryanodine receptor types 1 and 2. | 2009-01 |
|
| Enantiomeric enrichment of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) in mice after induction of CYP enzymes. | 2008-10 |
|
| 2,2',3,3',6,6'-Hexachlorobiphenyl (PCB 136) atropisomers interact enantioselectively with hepatic microsomal cytochrome P450 enzymes. | 2008-06 |
|
| Dose-dependent enantiomeric enrichment of 2,2',3,3',6,6'-hexachlorobiphenyl in female mice. | 2008-02 |
|
| Influence of dietary fat on the enantioselective disposition of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) in female mice. | 2008-02 |
|
| Enantioselective disposition of PCB 136 (2,2',3,3',6,6'-hexachlorobiphenyl) in C57BL/6 mice after oral and intraperitoneal administration. | 2007-01 |
|
| Structure-activity relationship for noncoplanar polychlorinated biphenyl congeners toward the ryanodine receptor-Ca2+ channel complex type 1 (RyR1). | 2006-01 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:50:57 GMT 2025
by
admin
on
Mon Mar 31 21:50:57 GMT 2025
|
| Record UNII |
MOA04J1VTW
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Systematic Name | English | ||
|
Preferred Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
MOA04J1VTW
Created by
admin on Mon Mar 31 21:50:57 GMT 2025 , Edited by admin on Mon Mar 31 21:50:57 GMT 2025
|
PRIMARY | |||
|
38411-22-2
Created by
admin on Mon Mar 31 21:50:57 GMT 2025 , Edited by admin on Mon Mar 31 21:50:57 GMT 2025
|
PRIMARY | |||
|
DTXSID6073499
Created by
admin on Mon Mar 31 21:50:57 GMT 2025 , Edited by admin on Mon Mar 31 21:50:57 GMT 2025
|
PRIMARY | |||
|
34199
Created by
admin on Mon Mar 31 21:50:57 GMT 2025 , Edited by admin on Mon Mar 31 21:50:57 GMT 2025
|
PRIMARY | |||
|
38024
Created by
admin on Mon Mar 31 21:50:57 GMT 2025 , Edited by admin on Mon Mar 31 21:50:57 GMT 2025
|
PRIMARY |