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Details

Stereochemistry ABSOLUTE
Molecular Formula C9H12BNO4
Molecular Weight 209.007
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of EPINEPHRYL BORATE

SMILES

CNC[C@H](O)C1=CC=C2OB(O)OC2=C1

InChI

InChIKey=ZNMXKJDERFMXNF-ZETCQYMHSA-N
InChI=1S/C9H12BNO4/c1-11-5-7(12)6-2-3-8-9(4-6)15-10(13)14-8/h2-4,7,11-13H,5H2,1H3/t7-/m0/s1

HIDE SMILES / InChI

Molecular Formula C9H12BNO4
Molecular Weight 209.007
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

EPINEPHRYL BORATE (Epinal®) is an epinephrine derivative, which reduces elevated intraocular pressure in chronic open-angle glaucoma. It may also be used in eye surgery.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Epinal

Approved Use

Reduces elevated intraocular pressure in chronic open-angle glaucoma
Doses

Doses

DosePopulationAdverse events​
1 % single, ophthalmic
Dose: 1 %
Route: ophthalmic
Route: single
Dose: 1 %
Sources:
healthy, adult
n = 20
Health Status: healthy
Condition: model of allergic conjunctivitis
Age Group: adult
Sex: unknown
Population Size: 20
Sources:

Sample Use Guides

Instill 1 drop into the eyes once or twice daily.
Route of Administration: Topical
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:10:45 GMT 2023
Edited
by admin
on Fri Dec 15 15:10:45 GMT 2023
Record UNII
MO99IGH0LS
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
EPINEPHRYL BORATE
USAN   USP   VANDF   WHO-DD  
USAN  
Official Name English
EPINEPHRYL BORATE [VANDF]
Common Name English
Epinephryl borate [WHO-DD]
Common Name English
(-)-3,4-DIHYDROXY-.ALPHA.-((METHYLAMINO)METHYL)BENZYL ALCOHOL, CYCLIC 3,4-ESTER WITH BORIC ACID
Common Name English
1,3,2-BENZODIOXABOROLE-5-METHANOL, 2-HYDROXY-.ALPHA.-((METHYLAMINO)METHYL)-, (R)-
Systematic Name English
EPINEPHRYL BORATE [USP IMPURITY]
Common Name English
EPINEPHRYL BORATE [USAN]
Common Name English
Code System Code Type Description
MESH
C018285
Created by admin on Fri Dec 15 15:10:45 GMT 2023 , Edited by admin on Fri Dec 15 15:10:45 GMT 2023
PRIMARY
NCI_THESAURUS
C174719
Created by admin on Fri Dec 15 15:10:45 GMT 2023 , Edited by admin on Fri Dec 15 15:10:45 GMT 2023
PRIMARY
RXCUI
24255
Created by admin on Fri Dec 15 15:10:45 GMT 2023 , Edited by admin on Fri Dec 15 15:10:45 GMT 2023
PRIMARY RxNorm
PUBCHEM
10242182
Created by admin on Fri Dec 15 15:10:45 GMT 2023 , Edited by admin on Fri Dec 15 15:10:45 GMT 2023
PRIMARY
FDA UNII
MO99IGH0LS
Created by admin on Fri Dec 15 15:10:45 GMT 2023 , Edited by admin on Fri Dec 15 15:10:45 GMT 2023
PRIMARY
EVMPD
SUB13690MIG
Created by admin on Fri Dec 15 15:10:45 GMT 2023 , Edited by admin on Fri Dec 15 15:10:45 GMT 2023
PRIMARY
CAS
5579-16-8
Created by admin on Fri Dec 15 15:10:45 GMT 2023 , Edited by admin on Fri Dec 15 15:10:45 GMT 2023
PRIMARY
SMS_ID
100000078928
Created by admin on Fri Dec 15 15:10:45 GMT 2023 , Edited by admin on Fri Dec 15 15:10:45 GMT 2023
PRIMARY
EPA CompTox
DTXSID50971170
Created by admin on Fri Dec 15 15:10:45 GMT 2023 , Edited by admin on Fri Dec 15 15:10:45 GMT 2023
PRIMARY
ECHA (EC/EINECS)
226-961-8
Created by admin on Fri Dec 15 15:10:45 GMT 2023 , Edited by admin on Fri Dec 15 15:10:45 GMT 2023
PRIMARY