U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C12HCl7O2
Molecular Weight 425.306
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1,2,3,4,6,7,8-HEPTACHLORODIBENZO-P-DIOXIN

SMILES

ClC1=CC2=C(OC3=C(Cl)C(Cl)=C(Cl)C(Cl)=C3O2)C(Cl)=C1Cl

InChI

InChIKey=WCLNVRQZUKYVAI-UHFFFAOYSA-N
InChI=1S/C12HCl7O2/c13-2-1-3-10(7(17)4(2)14)21-12-9(19)6(16)5(15)8(18)11(12)20-3/h1H

HIDE SMILES / InChI

Molecular Formula C12HCl7O2
Molecular Weight 425.306
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Consensus toxicity factors for polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls combining in silico models and extensive in vitro screening of AhR-mediated effects in human and rodent cells.
2015-04-20
Differential relative effect potencies of some dioxin-like compounds in human peripheral blood lymphocytes and murine splenic cells.
2014-04-07
Determination of some congeners of polychlorinated dibenzo-p-dioxins (PCDDs) in milk using gas chromatography.
2009-06
Prevalence of metabolic syndrome associated with body burden levels of dioxin and related compounds among Japan's general population.
2009-04
Association of organochlorine pesticides with peripheral neuropathy in patients with diabetes or impaired fasting glucose.
2008-11
Systems biological and mechanistic modelling of radiation-induced cancer.
2008-02
Association of serum concentrations of persistent organic pollutants with the prevalence of learning disability and attention deficit disorder.
2007-07
Dietary uptake of dioxins (PCDD/PCDFs) and dioxin-like PCBs in Spanish aquacultured turbot (Psetta maxima).
2007-04
Cytochrome P450 1A4 and 1A5 in common cormorant (Phalacrocorax carbo): evolutionary relationships and functional implications associated with dioxin and related compounds.
2006-08
A strong dose-response relation between serum concentrations of persistent organic pollutants and diabetes: results from the National Health and Examination Survey 1999-2002.
2006-07
Concentrations of PM(2.5)-associated OC, EC, and PCDD/Fs measured during the 2003 wildfire season in Missoula, Montana.
2006-04
Breast milk dioxins in Hong Kong and Pearl River Delta.
2006-02
Serum dioxin levels in former chlorophenol workers.
2006-01
Aryl hydrocarbon receptor (AHR) and AHR nuclear translocator (ARNT) expression in Baikal seal (Pusa sibirica) and association with 2,3,7,8-TCDD toxic equivalents and CYP1 expression levels.
2005-07
Exposures among pregnant women near the World Trade Center site on 11 September 2001.
2005-06
Chronic toxicity and carcinogenicity of 1,2,3,4,6,7,8-heptachlorodibenzo-p-dioxin displays a distinct dose/time toxicity threshold (c x t = k) and a life-prolonging subthreshold effect.
2005-05
Influence of chemical characteristics of humic substances on the partition coefficient of a chlorinated dioxin.
2005-03
Solid-phase microextraction for the evaluation of partition coefficients of a chlorinated dioxin and hexachlorobenzene into humic substances.
2004-05
Exposure assessment of residents living near a wood treatment plant.
2003-06
Half-lives of tetra-, penta-, hexa-, hepta-, and octachlorodibenzo-p-dioxin in rats, monkeys, and humans--a critical review.
2002-08
Polychlorinated dibenzo-p-dioxin and dibenzofuran concentrations in serum samples of workers at intermittently burning municipal waste incinerators in Japan.
2002-06
Structure-activity relationships and dose responses of polychlorinated dibenzo-p-dioxins for short-term effects in 2,3,7,8-tetrachlorodibenzo-p-dioxin-resistant and -sensitive rat strains.
2002-05-15
Phototransformation of polychlorinated dibenzo-p-dioxins from photolysis of pentachlorophenol on soils surface.
2002-03
Kinetics and inductive potency of 1,2,3,4,6,7,8-heptachlorodibenzo-p-dioxin (H7CDD) in rats.
2001-06-22
The role of time as a quantifiable variable of toxicity and the experimental conditions when Haber's c x t product can be observed: implications for therapeutics.
2001-03
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-mediated membrane translocation of c-Src protein kinase in liver WB-F344 cells.
1999-07-13
Patents

Patents

Substance Class Chemical
Created
by admin
on Mon Mar 31 18:52:02 GMT 2025
Edited
by admin
on Mon Mar 31 18:52:02 GMT 2025
Record UNII
MM6333103R
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
1,2,3,4,6,7,8-HEPTACHLORODIBENZO-P-DIOXIN
Common Name English
1,2,3,4,6,7,8-HPCDD
Preferred Name English
1,2,3,4,6,7,8-HEPTACHLORODIBENZODIOXIN
Systematic Name English
DIBENZO-P-DIOXIN, 1,2,3,4,6,7,8-HEPTACHLORO-
Common Name English
HEPTACHLORODIBENZO-P-DIOXIN [HSDB]
Common Name English
DIBENZO(B,E)(1,4)DIOXIN, 1,2,3,4,6,7,8-HEPTACHLORO-
Systematic Name English
PCDD 73
Common Name English
Code System Code Type Description
CAS
35822-46-9
Created by admin on Mon Mar 31 18:52:02 GMT 2025 , Edited by admin on Mon Mar 31 18:52:02 GMT 2025
PRIMARY
WIKIPEDIA
Heptachlorodibenzo-p-dioxin
Created by admin on Mon Mar 31 18:52:02 GMT 2025 , Edited by admin on Mon Mar 31 18:52:02 GMT 2025
PRIMARY
HSDB
6474
Created by admin on Mon Mar 31 18:52:02 GMT 2025 , Edited by admin on Mon Mar 31 18:52:02 GMT 2025
PRIMARY
MESH
C046839
Created by admin on Mon Mar 31 18:52:02 GMT 2025 , Edited by admin on Mon Mar 31 18:52:02 GMT 2025
PRIMARY
EPA CompTox
DTXSID1052034
Created by admin on Mon Mar 31 18:52:02 GMT 2025 , Edited by admin on Mon Mar 31 18:52:02 GMT 2025
PRIMARY
FDA UNII
MM6333103R
Created by admin on Mon Mar 31 18:52:02 GMT 2025 , Edited by admin on Mon Mar 31 18:52:02 GMT 2025
PRIMARY
PUBCHEM
37270
Created by admin on Mon Mar 31 18:52:02 GMT 2025 , Edited by admin on Mon Mar 31 18:52:02 GMT 2025
PRIMARY