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Details

Stereochemistry ACHIRAL
Molecular Formula Rb
Molecular Weight 85.4677
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of RUBIDIUM

SMILES

[RbH]

InChI

InChIKey=UCYFRLNGKNNHBD-UHFFFAOYSA-N
InChI=1S/Rb.H

HIDE SMILES / InChI

Molecular Formula Rb
Molecular Weight 85.4677
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

A soft metal that ignites in the air and reacts violently with water. Rubidium is little used outside research. It has been used as a component of photocells, to remove traces of oxygen from vacuum tubes and to make special types of glass. It is easily ionised so was considered for use in ion engines, but was found to be less effective than caesium. It has also been proposed for use as a working fluid for vapour turbines and in thermoelectric generators. Rubidium has no known biological role and is non-toxic. It is slightly radioactive and so has been used to locate brain tumours, as it collects in tumours but not in normal tissue. Rubidium is a component of marketed topical cream QBx (formerly Known As PHI-5, K041059). PHI-5 is a formulation containing zinc and rubidium ions, which is developed for treatment of chronic wounds. Commercially, PHI-5 is available as an impregnated wound dressing material (Dermax).

Approval Year

PubMed

PubMed

TitleDatePubMed
Functional expression of the cDNA encoded by the human ATP1AL1 gene.
1996 Sep
Functional and molecular characterization of the K-Cl cotransporter of Xenopus laevis oocytes.
2001 Aug
The transient receptor potential protein homologue TRP6 is the essential component of vascular alpha(1)-adrenoceptor-activated Ca(2+)-permeable cation channel.
2001 Feb 16
Functional identification of ion binding sites at the internal end of the pore in Shaker K+ channels.
2003 May 15
Alpha1-AR-mediated activation of NKCC in rat cardiomyocytes involves ERK-dependent phosphorylation of the cotransporter.
2004 Apr
Relationship between pore occupancy and gating in BK potassium channels.
2006 May
Intracellular potassium stabilizes human ether-à-go-go-related gene channels for export from endoplasmic reticulum.
2009 Apr
Identification of novel KCNQ4 openers by a high-throughput fluorescence-based thallium flux assay.
2011 Nov 1
Patents

Patents

Sample Use Guides

An in vivo study was performed on the effect of PHI-5 (Rubidium Chloride, Zinc Chloride ) on cutaneous wound healing in a guinea pig model. First, a standardized wound was created. The silicone substrates were sutured onto the wound, with the side containing PHI-5 making contact with the wound. Results showed a faster wound closure after 1 week, when 10 ug of PHI-5 was applied.
Route of Administration: Topical
Substance Class Chemical
Created
by admin
on Sat Jun 26 11:13:16 UTC 2021
Edited
by admin
on Sat Jun 26 11:13:16 UTC 2021
Record UNII
MLT4718TJW
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
RUBIDIUM
MI   WHO-DD  
Systematic Name English
RUBIDIUM, ELEMENTAL
Common Name English
RUBIDIUM METALLICUM
Common Name English
RUBIDIUM [WHO-DD]
Common Name English
RUBIDIUM [MI]
Common Name English
RB
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C637
Created by admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
DSLD 1946 (Number of products:63)
Created by admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
Code System Code Type Description
MESH
D012413
Created by admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
PRIMARY
EPA CompTox
7440-17-7
Created by admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
PRIMARY
NCI_THESAURUS
C95191
Created by admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
PRIMARY
MERCK INDEX
M9685
Created by admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
PRIMARY Merck Index
RXCUI
1311489
Created by admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
PRIMARY RxNorm
PUBCHEM
5357696
Created by admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
PRIMARY
FDA UNII
MLT4718TJW
Created by admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
PRIMARY
EVMPD
SUB15159MIG
Created by admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
PRIMARY
ECHA (EC/EINECS)
231-126-6
Created by admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
PRIMARY
DRUG BANK
DB11346
Created by admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
PRIMARY
CAS
7440-17-7
Created by admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
PRIMARY
Related Record Type Details
ACTIVE MOIETY