Details
Stereochemistry | ACHIRAL |
Molecular Formula | Rb |
Molecular Weight | 85.4677 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[RbH]
InChI
InChIKey=UCYFRLNGKNNHBD-UHFFFAOYSA-N
InChI=1S/Rb.H
Molecular Formula | Rb |
Molecular Weight | 85.4677 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
A soft metal that ignites in the air and reacts violently with water. Rubidium is little used outside research. It has been used as a component of photocells, to remove traces of oxygen from vacuum tubes and to make special types of glass. It is easily ionised so was considered for use in ion engines, but was found to be less effective than caesium. It has also been proposed for use as a working fluid for vapour turbines and in thermoelectric generators. Rubidium has no known biological role and is non-toxic. It is slightly radioactive and so has been used to locate brain tumours, as it collects in tumours but not in normal tissue. Rubidium is a component of marketed topical cream QBx (formerly Known As PHI-5, K041059). PHI-5 is a formulation containing zinc and rubidium ions, which is developed for treatment of chronic wounds. Commercially, PHI-5 is available as an impregnated wound dressing material (Dermax).
Originator
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Functional expression of the cDNA encoded by the human ATP1AL1 gene. | 1996 Sep |
|
Functional and molecular characterization of the K-Cl cotransporter of Xenopus laevis oocytes. | 2001 Aug |
|
The transient receptor potential protein homologue TRP6 is the essential component of vascular alpha(1)-adrenoceptor-activated Ca(2+)-permeable cation channel. | 2001 Feb 16 |
|
Functional identification of ion binding sites at the internal end of the pore in Shaker K+ channels. | 2003 May 15 |
|
Alpha1-AR-mediated activation of NKCC in rat cardiomyocytes involves ERK-dependent phosphorylation of the cotransporter. | 2004 Apr |
|
Relationship between pore occupancy and gating in BK potassium channels. | 2006 May |
|
Intracellular potassium stabilizes human ether-à-go-go-related gene channels for export from endoplasmic reticulum. | 2009 Apr |
|
Identification of novel KCNQ4 openers by a high-throughput fluorescence-based thallium flux assay. | 2011 Nov 1 |
Patents
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/17387598
An in vivo study was performed on the effect of PHI-5 (Rubidium Chloride, Zinc Chloride ) on cutaneous wound healing in a guinea pig model. First, a standardized wound was created. The silicone substrates were sutured onto the wound, with the side containing PHI-5 making contact with the wound. Results showed a faster wound closure after 1 week, when 10 ug of PHI-5 was applied.
Route of Administration:
Topical
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Jun 26 11:13:16 UTC 2021
by
admin
on
Sat Jun 26 11:13:16 UTC 2021
|
Record UNII |
MLT4718TJW
|
Record Status |
Validated (UNII)
|
Record Version |
|
-
Download
Name | Type | Language | ||
---|---|---|---|---|
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
Classification Tree | Code System | Code | ||
---|---|---|---|---|
|
NCI_THESAURUS |
C637
Created by
admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
|
||
|
DSLD |
1946 (Number of products:63)
Created by
admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
|
Code System | Code | Type | Description | ||
---|---|---|---|---|---|
|
D012413
Created by
admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
|
PRIMARY | |||
|
7440-17-7
Created by
admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
|
PRIMARY | |||
|
C95191
Created by
admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
|
PRIMARY | |||
|
M9685
Created by
admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
|
PRIMARY | Merck Index | ||
|
1311489
Created by
admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
|
PRIMARY | RxNorm | ||
|
5357696
Created by
admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
|
PRIMARY | |||
|
MLT4718TJW
Created by
admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
|
PRIMARY | |||
|
SUB15159MIG
Created by
admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
|
PRIMARY | |||
|
231-126-6
Created by
admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
|
PRIMARY | |||
|
DB11346
Created by
admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
|
PRIMARY | |||
|
7440-17-7
Created by
admin on Sat Jun 26 11:13:16 UTC 2021 , Edited by admin on Sat Jun 26 11:13:16 UTC 2021
|
PRIMARY |
Related Record | Type | Details | ||
---|---|---|---|---|
|
ACTIVE MOIETY |