Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | Rb |
| Molecular Weight | 85.4678 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Rb]
InChI
InChIKey=UCYFRLNGKNNHBD-UHFFFAOYSA-N
InChI=1S/Rb.H
| Molecular Formula | Rb |
| Molecular Weight | 85.4678 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
A soft metal that ignites in the air and reacts violently with water. Rubidium is little used outside research. It has been used as a component of photocells, to remove traces of oxygen from vacuum tubes and to make special types of glass. It is easily ionised so was considered for use in ion engines, but was found to be less effective than caesium. It has also been proposed for use as a working fluid for vapour turbines and in thermoelectric generators. Rubidium has no known biological role and is non-toxic. It is slightly radioactive and so has been used to locate brain tumours, as it collects in tumours but not in normal tissue. Rubidium is a component of marketed topical cream QBx (formerly Known As PHI-5, K041059). PHI-5 is a formulation containing zinc and rubidium ions, which is developed for treatment of chronic wounds. Commercially, PHI-5 is available as an impregnated wound dressing material (Dermax).
Originator
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Identification of novel KCNQ4 openers by a high-throughput fluorescence-based thallium flux assay. | 2011-11-01 |
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| Intracellular potassium stabilizes human ether-à-go-go-related gene channels for export from endoplasmic reticulum. | 2009-04 |
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| Relationship between pore occupancy and gating in BK potassium channels. | 2006-05 |
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| Alpha1-AR-mediated activation of NKCC in rat cardiomyocytes involves ERK-dependent phosphorylation of the cotransporter. | 2004-04 |
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| Functional identification of ion binding sites at the internal end of the pore in Shaker K+ channels. | 2003-05-15 |
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| Functional and molecular characterization of the K-Cl cotransporter of Xenopus laevis oocytes. | 2001-08 |
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| The transient receptor potential protein homologue TRP6 is the essential component of vascular alpha(1)-adrenoceptor-activated Ca(2+)-permeable cation channel. | 2001-02-16 |
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| Functional expression of the cDNA encoded by the human ATP1AL1 gene. | 1996-09 |
Patents
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/17387598
An in vivo study was performed on the effect of PHI-5 (Rubidium Chloride, Zinc Chloride ) on cutaneous wound healing in a guinea pig model. First, a standardized wound was created. The silicone substrates were sutured onto the wound, with the side containing PHI-5 making contact with the wound. Results showed a faster wound closure after 1 week, when 10 ug of PHI-5 was applied.
Route of Administration:
Topical
| Substance Class |
Chemical
Created
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| Record UNII |
MLT4718TJW
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| Record Status |
Validated (UNII)
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C637
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DSLD |
1946 (Number of products:63)
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D012413
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100000078860
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DTXSID4064686
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C95191
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m9685
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Rubidium
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33322
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1311489
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5357696
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MLT4718TJW
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SUB15159MIG
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231-126-6
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DB11346
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7440-17-7
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ACTIVE MOIETY |