Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C3H7NO |
| Molecular Weight | 73.0938 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NCCC=O
InChI
InChIKey=PCXDJQZLDDHMGX-UHFFFAOYSA-N
InChI=1S/C3H7NO/c4-2-1-3-5/h3H,1-2,4H2
| Molecular Formula | C3H7NO |
| Molecular Weight | 73.0938 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Purification and characterization of aminopropionaldehyde dehydrogenase from Arthrobacter sp. TMP-1. | 2001 Feb 20 |
|
| Polyamine cytotoxicity in the presence of bovine serum amine oxidase. | 2001 Mar 23 |
|
| Metabolism of polyamine oxidation products in plants: localisation of pea aminoaldehyde dehydrogenase activity. | 2002 Apr |
|
| tan and ebony genes regulate a novel pathway for transmitter metabolism at fly photoreceptor terminals. | 2002 Dec 15 |
|
| Purification and characterization of aminobutyraldehyde dehydrogenase from Arthrobacter Sp. TMP-1. | 2002 Jun |
|
| Carnosine is a quencher of 4-hydroxy-nonenal: through what mechanism of reaction? | 2002 Nov 15 |
|
| Purification and properties of betaine aldehyde dehydrogenase from Avena sativa. | 2003 Apr |
|
| Yeast Fms1 is a FAD-utilizing polyamine oxidase. | 2003 Apr 11 |
|
| 3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin. | 2003 Apr 15 |
|
| Heterologous expression and characterization of mouse spermine oxidase. | 2003 Feb 14 |
|
| Specialization of function among aldehyde dehydrogenases: the ALD2 and ALD3 genes are required for beta-alanine biosynthesis in Saccharomyces cerevisiae. | 2003 Jan |
|
| 3-Aminopropanal is a lysosomotropic aldehyde that causes oxidative stress and apoptosis by rupturing lysosomes. | 2003 Jun |
|
| Ebony, a novel nonribosomal peptide synthetase for beta-alanine conjugation with biogenic amines in Drosophila. | 2003 Oct 17 |
|
| Design, synthesis and analysis of a pyrrolepolyamide-nucleoside hybrid. | 2004 |
|
| Human neuroblastoma (SH-SY5Y) cells are highly sensitive to the lysosomotropic aldehyde 3-aminopropanal. | 2004 Aug 6 |
|
| Metabolism of monoamines in invertebrates: the relative importance of monoamine oxidase in different phyla. | 2004 Jan |
|
| Cleavage of the peptide bond of beta-alanyl-L-histidine (carnosine) induced by a Co(III)-amine complexes: reaction, structure and mechanism. | 2004 May 7 |
|
| Constitutive activity of N-beta-alanyl-catecholamine ligase in insect brain. | 2004 Sep 23 |
|
| Developing high affinity oligosaccharide inhibitors: conformational pre-organization paired with functional group modification. | 2005 Aug 7 |
|
| The design, synthesis and evaluation of high affinity macrocyclic carbohydrate inhibitors. | 2005 Aug 7 |
|
| Molecular characterization of the ebony gene from the American cockroach, Periplaneta americana. | 2005 Jul |
|
| [New oxaanalogues of spermine]. | 2005 Mar-Apr |
|
| Crystal structures of Fms1 and its complex with spermine reveal substrate specificity. | 2005 May 13 |
|
| Isolation of cDNA and enzymatic properties of betaine aldehyde dehydrogenase from Zoysia tenuifolia. | 2005 Oct |
|
| QSAR study on carbonic anhydrase inhibitors: water-soluble sulfonamides incorporating beta-alanyl moieties, possessing long lasting-intra ocular pressure lowering properties--a molecular connectivity approach. | 2005 Oct |
|
| Characterization and a role of Pseudomonas aeruginosa spermidine dehydrogenase in polyamine catabolism. | 2006 Aug |
|
| Orthogonally protected cyclo-beta-tetrapeptides as solid-supported scaffolds for the synthesis of glycoclusters. | 2006 Mar 3 |
|
| Aldehyde load in ischemia-reperfusion brain injury: neuroprotection by neutralization of reactive aldehydes with phenelzine. | 2006 Nov 29 |
|
| Synthesis and evaluation of 3-aminopropionyl substituted fentanyl analogues for opioid activity. | 2006 Sep 15 |
|
| The concept of "aldehyde load" in neurodegenerative mechanisms: cytotoxicity of the polyamine degradation products hydrogen peroxide, acrolein, 3-aminopropanal, 3-acetamidopropanal and 4-aminobutanal in a retinal ganglion cell line. | 2007 May 11 |
|
| Lysosomes in iron metabolism, ageing and apoptosis. | 2008 Apr |
|
| Synthesis and testing of chromogenic phenoxazinone substrates for beta-alanyl aminopeptidase. | 2008 Feb 21 |
|
| Badh2, encoding betaine aldehyde dehydrogenase, inhibits the biosynthesis of 2-acetyl-1-pyrroline, a major component in rice fragrance. | 2008 Jul |
|
| Enzymatic characterization of peroxisomal and cytosolic betaine aldehyde dehydrogenases in barley. | 2008 Sep |
|
| Niemann-Pick C1 functions in regulating lysosomal amine content. | 2008 Sep 5 |
|
| Increased spermine oxidase (SMO) activity as a novel differentiation marker of myogenic C2C12 cells. | 2009 Apr |
|
| The role of polyamine metabolism in neuronal injury following cerebral ischemia. | 2009 Jan |
|
| Design, synthesis, and analysis of minor groove binder pyrrolepolyamide-2'-deoxyguanosine hybrids. | 2010 |
|
| Phosphorus-nitrogen compounds. 21. Syntheses, structural investigations, biological activities, and DNA interactions of new N/O spirocyclic phosphazene derivatives. The NMR behaviors of chiral phosphazenes with stereogenic centers upon the addition of chiral solvating agents. | 2010 Aug 2 |
|
| Mechanistic studies of the yeast polyamine oxidase Fms1: kinetic mechanism, substrate specificity, and pH dependence. | 2010 Dec 14 |
|
| The effect of carnosine treatment on prooxidant-antioxidant balance in liver, heart and brain tissues of male aged rats. | 2010 Feb |
|
| Mechanistic studies of human spermine oxidase: kinetic mechanism and pH effects. | 2010 Jan 19 |
|
| A phase I clinical trial of tiopronin, a putative neuroprotective agent, in aneurysmal subarachnoid hemorrhage. | 2010 Jul |
|
| [Design, synthesis and evaluation of polyamide-nucleoside hybrids and oligonucleotides conjugated hybrid as a novel gene expression control compound]. | 2010 Mar |
|
| Role of nutritional zinc in the prevention of osteoporosis. | 2010 May |
|
| Beta-alanyl peptide synthesis by Streptomyces S9 aminopeptidase. | 2010 May 3 |
|
| Synthesis and splice-redirecting activity of branched, arginine-rich peptide dendrimer conjugates of peptide nucleic acid oligonucleotides. | 2010 Oct 20 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 18:23:03 GMT 2023
by
admin
on
Fri Dec 15 18:23:03 GMT 2023
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| Record UNII |
ML707Y407U
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| Record Status |
Validated (UNII)
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| Record Version |
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352-92-1
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