U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C3H7NO
Molecular Weight 73.0938
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 3-AMINOPROPANAL

SMILES

NCCC=O

InChI

InChIKey=PCXDJQZLDDHMGX-UHFFFAOYSA-N
InChI=1S/C3H7NO/c4-2-1-3-5/h3H,1-2,4H2

HIDE SMILES / InChI

Molecular Formula C3H7NO
Molecular Weight 73.0938
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Mechanistic studies of the yeast polyamine oxidase Fms1: kinetic mechanism, substrate specificity, and pH dependence.
2010-12-14
Synthesis and splice-redirecting activity of branched, arginine-rich peptide dendrimer conjugates of peptide nucleic acid oligonucleotides.
2010-10-20
Phosphorus-nitrogen compounds. 21. Syntheses, structural investigations, biological activities, and DNA interactions of new N/O spirocyclic phosphazene derivatives. The NMR behaviors of chiral phosphazenes with stereogenic centers upon the addition of chiral solvating agents.
2010-08-02
A phase I clinical trial of tiopronin, a putative neuroprotective agent, in aneurysmal subarachnoid hemorrhage.
2010-07
Beta-alanyl peptide synthesis by Streptomyces S9 aminopeptidase.
2010-05-03
Role of nutritional zinc in the prevention of osteoporosis.
2010-05
[Design, synthesis and evaluation of polyamide-nucleoside hybrids and oligonucleotides conjugated hybrid as a novel gene expression control compound].
2010-03
The effect of carnosine treatment on prooxidant-antioxidant balance in liver, heart and brain tissues of male aged rats.
2010-02
Mechanistic studies of human spermine oxidase: kinetic mechanism and pH effects.
2010-01-19
Design, synthesis, and analysis of minor groove binder pyrrolepolyamide-2'-deoxyguanosine hybrids.
2010
Increased spermine oxidase (SMO) activity as a novel differentiation marker of myogenic C2C12 cells.
2009-04
The role of polyamine metabolism in neuronal injury following cerebral ischemia.
2009-01
Niemann-Pick C1 functions in regulating lysosomal amine content.
2008-09-05
Enzymatic characterization of peroxisomal and cytosolic betaine aldehyde dehydrogenases in barley.
2008-09
Badh2, encoding betaine aldehyde dehydrogenase, inhibits the biosynthesis of 2-acetyl-1-pyrroline, a major component in rice fragrance.
2008-07
Lysosomes in iron metabolism, ageing and apoptosis.
2008-04
Synthesis and testing of chromogenic phenoxazinone substrates for beta-alanyl aminopeptidase.
2008-02-21
The concept of "aldehyde load" in neurodegenerative mechanisms: cytotoxicity of the polyamine degradation products hydrogen peroxide, acrolein, 3-aminopropanal, 3-acetamidopropanal and 4-aminobutanal in a retinal ganglion cell line.
2007-05-11
Aldehyde load in ischemia-reperfusion brain injury: neuroprotection by neutralization of reactive aldehydes with phenelzine.
2006-11-29
Synthesis and evaluation of 3-aminopropionyl substituted fentanyl analogues for opioid activity.
2006-09-15
Characterization and a role of Pseudomonas aeruginosa spermidine dehydrogenase in polyamine catabolism.
2006-08
Orthogonally protected cyclo-beta-tetrapeptides as solid-supported scaffolds for the synthesis of glycoclusters.
2006-03-03
Isolation of cDNA and enzymatic properties of betaine aldehyde dehydrogenase from Zoysia tenuifolia.
2005-10
QSAR study on carbonic anhydrase inhibitors: water-soluble sulfonamides incorporating beta-alanyl moieties, possessing long lasting-intra ocular pressure lowering properties--a molecular connectivity approach.
2005-10
Developing high affinity oligosaccharide inhibitors: conformational pre-organization paired with functional group modification.
2005-08-07
The design, synthesis and evaluation of high affinity macrocyclic carbohydrate inhibitors.
2005-08-07
Molecular characterization of the ebony gene from the American cockroach, Periplaneta americana.
2005-07
[New oxaanalogues of spermine].
2005-05-14
Crystal structures of Fms1 and its complex with spermine reveal substrate specificity.
2005-05-13
Constitutive activity of N-beta-alanyl-catecholamine ligase in insect brain.
2004-09-23
Human neuroblastoma (SH-SY5Y) cells are highly sensitive to the lysosomotropic aldehyde 3-aminopropanal.
2004-08-06
Cleavage of the peptide bond of beta-alanyl-L-histidine (carnosine) induced by a Co(III)-amine complexes: reaction, structure and mechanism.
2004-05-07
Metabolism of monoamines in invertebrates: the relative importance of monoamine oxidase in different phyla.
2004-01
Design, synthesis and analysis of a pyrrolepolyamide-nucleoside hybrid.
2004
Ebony, a novel nonribosomal peptide synthetase for beta-alanine conjugation with biogenic amines in Drosophila.
2003-10-17
3-Aminopropanal is a lysosomotropic aldehyde that causes oxidative stress and apoptosis by rupturing lysosomes.
2003-06
3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin.
2003-04-15
Yeast Fms1 is a FAD-utilizing polyamine oxidase.
2003-04-11
Purification and properties of betaine aldehyde dehydrogenase from Avena sativa.
2003-04
Heterologous expression and characterization of mouse spermine oxidase.
2003-02-14
Specialization of function among aldehyde dehydrogenases: the ALD2 and ALD3 genes are required for beta-alanine biosynthesis in Saccharomyces cerevisiae.
2003-01
tan and ebony genes regulate a novel pathway for transmitter metabolism at fly photoreceptor terminals.
2002-12-15
Carnosine is a quencher of 4-hydroxy-nonenal: through what mechanism of reaction?
2002-11-15
Purification and characterization of aminobutyraldehyde dehydrogenase from Arthrobacter Sp. TMP-1.
2002-06
Metabolism of polyamine oxidation products in plants: localisation of pea aminoaldehyde dehydrogenase activity.
2002-04
Polyamine cytotoxicity in the presence of bovine serum amine oxidase.
2001-03-23
Purification and characterization of aminopropionaldehyde dehydrogenase from Arthrobacter sp. TMP-1.
2001-02-20
Patents

Patents

Substance Class Chemical
Created
by admin
on Mon Mar 31 19:11:55 GMT 2025
Edited
by admin
on Mon Mar 31 19:11:55 GMT 2025
Record UNII
ML707Y407U
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
3-AMINOPROPANAL
Systematic Name English
.BETA.-AMINOPROPIONALDEHYDE
Preferred Name English
3-AMINOPROPIONALDEHYDE
Systematic Name English
PROPANAL, 3-AMINO-
Systematic Name English
Code System Code Type Description
CHEBI
58374
Created by admin on Mon Mar 31 19:11:55 GMT 2025 , Edited by admin on Mon Mar 31 19:11:55 GMT 2025
PRIMARY
PUBCHEM
75
Created by admin on Mon Mar 31 19:11:55 GMT 2025 , Edited by admin on Mon Mar 31 19:11:55 GMT 2025
PRIMARY
CHEBI
18090
Created by admin on Mon Mar 31 19:11:55 GMT 2025 , Edited by admin on Mon Mar 31 19:11:55 GMT 2025
PRIMARY
EPA CompTox
DTXSID10188702
Created by admin on Mon Mar 31 19:11:55 GMT 2025 , Edited by admin on Mon Mar 31 19:11:55 GMT 2025
PRIMARY
FDA UNII
ML707Y407U
Created by admin on Mon Mar 31 19:11:55 GMT 2025 , Edited by admin on Mon Mar 31 19:11:55 GMT 2025
PRIMARY
MESH
C050862
Created by admin on Mon Mar 31 19:11:55 GMT 2025 , Edited by admin on Mon Mar 31 19:11:55 GMT 2025
PRIMARY
CAS
352-92-1
Created by admin on Mon Mar 31 19:11:55 GMT 2025 , Edited by admin on Mon Mar 31 19:11:55 GMT 2025
PRIMARY