FLUCLORONIDE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C24H29Cl2FO5
Molecular Weight	487.388
Optical Activity	UNSPECIFIED
Defined Stereocenters	9 / 9
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(Cl)[C@@H](Cl)C[C@]3(C)[C@@]2(O1)C(=O)CO

InChI

InChIKey=NJNWEGFJCGYWQT-VSXGLTOVSA-N

InChI=1S/C24H29Cl2FO5/c1-20(2)31-19-9-13-14-8-16(27)15-7-12(29)5-6-21(15,3)23(14,26)17(25)10-22(13,4)24(19,32-20)18(30)11-28/h5-7,13-14,16-17,19,28H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,21-,22-,23-,24+/m0/s1

HIDE SMILES / InChI

Molecular Formula	C24H29Cl2FO5
Molecular Weight	487.388
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	9 / 9
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5083443 | https://www.ncbi.nlm.nih.gov/pubmed/4612753 | (2013) Pharmeceutical manufacturing encyclopedia, page 1634, retrieved from: https://books.google.ru/books?id=_J2ti4EkYpkC

Flucloronide is a glucocorticoid. Fluclorolone acetonide is used for the palliative treatment of psoriasis and skin diseases.

Approval Year

PubMed

Title	Date	PubMed
Long-term treatment with 0-01% fluclorolone acetonide in children.	1976-03-13	1252855

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:50:38 GMT 2025` Edited by `admin` on `Mon Mar 31 18:50:38 GMT 2025`
Record UNII	MG258KTA37
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FLUCLORONIDE

Official Name

English

FLUCLOROLONE ACETONIDE

Preferred Name

English

FLUCLORONIDE [MI]

Common Name

English

fluclorolone acetonide [INN]

Common Name

English

9,11?-Dichloro-6?-fluoro-16?,17,21-trihydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone

Common Name

English

PREGNA-1,4-DIENE-3,20-DIONE, 9,11-DICHLORO-6-FLUORO-21-HYDROXY-16,17-((1-METHYLETHYLIDENE)BIS(OXY))-, (6.ALPHA.,11.BETA.,16.ALPHA.)-

Common Name

English

FLUCLORONIDE [USAN]

Common Name

English

FLUCLOROLONE ACETONIDE [MART.]

Common Name

English

Fluclorolone acetonide [WHO-DD]

Common Name

English

RS-2252

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C521