U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Dec 16 16:35:13 GMT 2023
Edited
by admin
on Sat Dec 16 16:35:13 GMT 2023
Source Materials Class ORGANISM
Source Materials Type RECOMBINANT VIRUS
Source Materials State LIVE NON-REPLICATING GENETICALLY MODIFIED
Organism Family Parvoviridae
Organism Genus Dependovirus
Organism Species adeno-associated virus
Author NONE
Infraspecific Type RECOMBINANT VECTOR
Infraspecific Name AAV.7m8-aflibercept
Part WHOLE
Record UNII
MFB3FSW75U
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Ixoberogene Soroparvovec
INN   USAN  
Official Name English
IXOBEROGENE SOROPARVOVEC [USAN]
Common Name English
ADVM-022
Code English
DNA (RECOMBINANT ADENO-ASSOCIATED VIRUS VECTOR ADVM-022 HUMAN CYTOMEGALOVIRUS PROMOTER PLUS (1-26)-(129-232)-HUMAN VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 FUSION PROTEIN WITH 227-327-HUMAN VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 FUSION PROTEI
Common Name English
ixoberogene soroparvovec [INN]
Common Name English
Code System Code Type Description
NCI_THESAURUS
C186407
Created by admin on Sat Dec 16 16:35:14 GMT 2023 , Edited by admin on Sat Dec 16 16:35:14 GMT 2023
PRIMARY
CAS
2538429-16-0
Created by admin on Sat Dec 16 16:35:14 GMT 2023 , Edited by admin on Sat Dec 16 16:35:14 GMT 2023
PRIMARY
USAN
JK-68
Created by admin on Sat Dec 16 16:35:14 GMT 2023 , Edited by admin on Sat Dec 16 16:35:14 GMT 2023
PRIMARY
FDA UNII
MFB3FSW75U
Created by admin on Sat Dec 16 16:35:14 GMT 2023 , Edited by admin on Sat Dec 16 16:35:14 GMT 2023
PRIMARY
INN
12109
Created by admin on Sat Dec 16 16:35:14 GMT 2023 , Edited by admin on Sat Dec 16 16:35:14 GMT 2023
PRIMARY
Related Record Type Details
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
VECTOR EXPRESSED PROTEIN UNSPECIFIED SUBSTANCE
7b9b358d
(not in database)