U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 11:55:40 GMT 2023
Edited
by admin
on Sat Dec 16 11:55:40 GMT 2023
Protein Sub Type
Sequence Type COMPLETE
Record UNII
MEG7LMR9E8
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TOLL-LIKE RECEPTOR 2
Common Name English
TOLL/INTERLEUKIN-1 RECEPTOR-LIKE PROTEIN 4
Common Name English
CD282
Common Name English
CD-282
Common Name English
TIL4
Common Name English
TLR2
Common Name English
Code System Code Type Description
FDA UNII
MEG7LMR9E8
Created by admin on Sat Dec 16 11:55:41 GMT 2023 , Edited by admin on Sat Dec 16 11:55:41 GMT 2023
PRIMARY
UNIPROT
O60603
Created by admin on Sat Dec 16 11:55:41 GMT 2023 , Edited by admin on Sat Dec 16 11:55:41 GMT 2023
PRIMARY
From To
1_10 1_16
1_333 1_362
1_412 1_434
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_94
N 1_179
N 1_394
N 1_422
Related Record Type Details
AGONIST -> TARGET
AGONIST -> TARGET
INHIBITOR -> TARGET
OPN-305 binds to the ligand-binding site on the TLR2 receptor and blocks the activation of TLR2-mediated innate immunity signaling.
INHIBITOR
AGONIST -> TARGET
AGONIST -> TARGET
AGONIST -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT CHEMICAL