BENDAZOL HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H12N2.ClH
Molecular Weight	244.719
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.C(C1=NC2=C(N1)C=CC=C2)C3=CC=CC=C3

InChI

InChIKey=CJTQARUHALKPGG-UHFFFAOYSA-N

InChI=1S/C14H12N2.ClH/c1-2-6-11(7-3-1)10-14-15-12-8-4-5-9-13(12)16-14;/h1-9H,10H2,(H,15,16);1H

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C14H12N2
Molecular Weight	208.2585
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.vidal.ru/drugs/bendazol

Bendazol (or dibazol), a vasodilator that used in Russia. This drug is indicated for the treatment of arterial hypertension, hypertensive crisis, spasms of internal organs (stomach ulcer, intestinal spasms), and diseases of the nervous system: residual effects of poliomyelitis. Bendazol lowers blood pressure by reducing cardiac output and expansion of peripheral vessels.

Approval Year

PubMed

Title	Date	PubMed
Bis(2-benzyl-1H-benzimidazole-N3)dichlorozinc(II).	2001 Jan	11173393
Substituent effects on enthalpies of formation of nitrogen heterocycles: 2-substituted benzimidazoles and related compounds.	2006 Feb 23	16480315
1,3-Bis(1-benzyl-1H-benzimidazol-2-yl)-2-oxapropane.	2009 Apr 10	21583837
Bis[1,3-bis-(1-benzyl-1H-benzimidazol-2-yl)-2-oxapropane]zinc(II) dipicrate dimethyl-formamide disolvate.	2009 Jun 17	21582714

Sample Use Guides

In Vivo Use Guide

peripheral facial nerve palsy, polyneuritis. hypertensive crisis – intravenous or intramuscular: 30-40 mg. arterial hypertension with a significant increase in blood pressure – intramuscular: 20-30 mg 2-3 times / day, the course: 8-14 days. nervous diseases: adults: 5 mg 1 time/day

Route of Administration: Other

Substance Class	Chemical Created by `admin` on `Sat Dec 16 01:28:24 GMT 2023` Edited by `admin` on `Sat Dec 16 01:28:24 GMT 2023`
Record UNII	ME751TL810
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BENDAZOL HYDROCHLORIDE

Common Name

English

BENDAZOL HYDROCHLORIDE [MI]

Common Name

English

DIBAZOL HYDROCHLORIDE

Common Name

English

1H-BENZIMIDAZOLE, 2-(PHENYLMETHYL)-, HYDROCHLORIDE (1:1)

Systematic Name

English

DIBAZOLE HYDROCHLORIDE

Common Name

English

Bendazol hydrochloride [WHO-DD]

Common Name

English

Code System Code Type Description

MERCK INDEX

m67