Retogatein

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 19:17:49 GMT 2025` Edited by `admin` on `Wed Apr 02 19:17:49 GMT 2025`
Protein Type	ENZYME
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	ME3BUS4RYT
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

2-585-Glutamate decarboxylase 2 (human clone rhGAD65)

Preferred Name

English

Retogatein

Common Name

English

retogatein [INN]

Common Name

English

N<sup>2.1</sup>-acetyl-[des-N-terminal methionyl]-glutamate decarboxylase 2 (Homo sapiens) (GAD2, 65 kDa glutamic acid decarboxylase, glutamate decarboxylase 65 kDa isoform, GAD65, EC:4.1.1.15), produced in Spodoptera frugiperda insect cells (cell line S

Common Name

English

Code System Code Type Description

INN

13133

Created by admin on Wed Apr 02 19:17:49 GMT 2025 , Edited by admin on Wed Apr 02 19:17:49 GMT 2025

PRIMARY

CAS

2938906-46-6

Created by admin on Wed Apr 02 19:17:49 GMT 2025 , Edited by admin on Wed Apr 02 19:17:49 GMT 2025

PRIMARY

FDA UNII

ME3BUS4RYT

Created by admin on Wed Apr 02 19:17:49 GMT 2025 , Edited by admin on Wed Apr 02 19:17:49 GMT 2025

PRIMARY

Related Record Type Details


					I7YY5T4995

GLUTAMATE DECARBOXYLASE 2

PARENT -> DERIVATIVE

Amount:

Related Record Type Details


					ME3BUS4RYT

Retogatein

ACTIVE MOIETY

Comments:

Immunomodulator

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_395]	SITE_SPECIFIC	K		N6-(PYRIDOXAL PHOSPHATE)LYSINE	QM00M3504A
AMINO_ACID_SUBSTITUTION	[1_1]	N-TERMINUS	A		N-ACETYLALANINE	26C4VY6Z0M

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL