Roconkibart

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 20:11:18 GMT 2023` Edited by `admin` on `Sat Dec 16 20:11:18 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	MD885NVL3Q
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Roconkibart

Official Name

English

JS-005

Code

English

JS005

Code

English

gamma4 heavy chain (1-444) [VH (Homo sapiens IGHV1-2*02(85.6%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.10] (26-33.51-58.97-106)) (1-117)-Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1 (118-215), hinge 1-12 S10>P (225) (216-227),CH2 L92 (306) (22

Common Name

English

Immunoglobulin G4 [225-proline], anti-(human interleukin 17A) (human-Mus musculus monoclonal JS005 γ4-chain), disulfide with human-Mus musculus monoclonal JS005 κ-chain, dimer

Common Name

English

Immunoglobulin G4-kappa, anti-[Homo sapiens IL17A (interleukin 17A, IL-17A)], monoclonal antibody

Common Name

English

roconkibart [INN]

Common Name

English

Code System Code Type Description

CAS

2638480-59-6

Created by admin on Sat Dec 16 20:11:18 GMT 2023 , Edited by admin on Sat Dec 16 20:11:18 GMT 2023

PRIMARY

FDA UNII

MD885NVL3Q

Created by admin on Sat Dec 16 20:11:18 GMT 2023 , Edited by admin on Sat Dec 16 20:11:18 GMT 2023

PRIMARY

INN

12736

Created by admin on Sat Dec 16 20:11:18 GMT 2023 , Edited by admin on Sat Dec 16 20:11:18 GMT 2023

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_131	4_219
2_144	2_200
2_258	2_318
1_131	3_219
2_364	2_422
3_23	3_93
3_139	3_199
4_23	4_93
4_139	4_199
1_144	1_200
1_223	2_223
1_226	2_226
1_258	1_318
1_364	1_422

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_294
N	2_294

Related Record Type Details


					R44E6C7B6J

INTERLEUKIN-17A

TARGET->LIGAND

Amount:

Related Record Type Details


					MD885NVL3Q

Roconkibart

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL