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Details

Stereochemistry RACEMIC
Molecular Formula C15H9O5S.Na
Molecular Weight 324.284
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TIXANOX SODIUM

SMILES

[Na+].C[S+]([O-])C1=CC=C2OC3=C(C=C(C=C3)C([O-])=O)C(=O)C2=C1

InChI

InChIKey=XDRMYCKQCFLSEG-UHFFFAOYSA-M
InChI=1S/C15H10O5S.Na/c1-21(19)9-3-5-13-11(7-9)14(16)10-6-8(15(17)18)2-4-12(10)20-13;/h2-7H,1H3,(H,17,18);/q;+1/p-1

HIDE SMILES / InChI
Molecular Formula C15H9O5S
Molecular Weight 301.294
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Tixanox is an antiallergic drug. It blocks histamine release from human lung induced by anti-IgE. Tixanox has been shown to be orally active against exercise-induced asthma in man.

Approval Year

Unknown
139594
PubMed

PubMed

TitleDatePubMed
Dibenzotropone- and dibenzosuberonecarboxylic acids with bronchodilator activity.
1979 Nov
Synthesis and aldose reductase inhibitory activity of 7-sulfamoylxanthone-2-carboxylic acids.
1980 Nov
The activity of sodium cromoglycate analogues in human lung in vitro: a comparison with rat passive cutaneous anaphylaxis and clinical efficacy.
1980 Oct
Reaction of 1-O-acyl glucuronides with 4-(p-nitrobenzyl)pyridine.
1986 Mar-Apr
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:32:13 GMT 2023
Edited
by admin
on Fri Dec 15 15:32:13 GMT 2023
Record UNII
MCN074529C
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TIXANOX SODIUM
Common Name English
9H-XANTHENE-2-CARBOXYLIC ACID, 7-(METHYLSULFINYL)-9-OXO-, SODIUM SALT
Common Name English
RS-7540
Code English
9H-XANTHENE-2-CARBOXYLIC ACID, 7-(METHYLSULFINYL)-9-OXO-, SODIUM SALT (1:1)
Systematic Name English
SODIUM 7-METHYLSULFINYLXANTHONE-2-CARBOXYLATE
Systematic Name English
Code System Code Type Description
EPA CompTox
DTXSID70961093
Created by admin on Fri Dec 15 15:32:13 GMT 2023 , Edited by admin on Fri Dec 15 15:32:13 GMT 2023
PRIMARY
FDA UNII
MCN074529C
Created by admin on Fri Dec 15 15:32:13 GMT 2023 , Edited by admin on Fri Dec 15 15:32:13 GMT 2023
PRIMARY
PUBCHEM
23712883
Created by admin on Fri Dec 15 15:32:13 GMT 2023 , Edited by admin on Fri Dec 15 15:32:13 GMT 2023
PRIMARY
CAS
40691-57-4
Created by admin on Fri Dec 15 15:32:13 GMT 2023 , Edited by admin on Fri Dec 15 15:32:13 GMT 2023
PRIMARY
Related Record Type Details
Structure of TIXANOX
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of TIXANOX
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