DIETHYLHEXYL ADIPATE

Details

Stereochemistry	MIXED
Molecular Formula	C22H42O4
Molecular Weight	370.5665
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCC(CC)COC(=O)CCCCC(=O)OCC(CC)CCCC

InChI

InChIKey=SAOKZLXYCUGLFA-UHFFFAOYSA-N

InChI=1S/C22H42O4/c1-5-9-13-19(7-3)17-25-21(23)15-11-12-16-22(24)26-18-20(8-4)14-10-6-2/h19-20H,5-18H2,1-4H3

HIDE SMILES / InChI

Molecular Formula	C22H42O4
Molecular Weight	370.5665
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Simultaneous determination of phthalates and adipates in human serum using gas chromatography-mass spectrometry with solid-phase extraction.	2010-10	20352652
Semivolatile endocrine-disrupting compounds in paired indoor and outdoor air in two northern California communities.	2010-09-01	20681565
Bioactive secondary metabolites from a new terrestrial Streptomyces sp. TN262.	2010-09	19842066
Dietary intake is associated with phthalate body burden in a nationally representative sample.	2010-07	20392686
PPARalpha: energy combustion, hypolipidemia, inflammation and cancer.	2010-04-16	20414453
Development of a gas chromatographic/mass spectrometric method for determination of phthalates in oily foods.	2010-03-26	20334193
Rapid identification of additives in poly(vinyl chloride) lid gaskets by direct analysis in real time ionisation and single-quadrupole mass spectrometry.	2010-01	19957297
Comparison of solidification of floating drop and homogenous liquid-liquid microextractions for the extraction of two plasticizers from the water kept in PET-bottles.	2009-09	19746401
Effects of plasticizers and their mixtures on estrogen receptor and thyroid hormone functions.	2009-08-25	19463926
Estrogenicity of food-associated estrogenic compounds in the fetuses of female transgenic mice upon oral and IP maternal exposure.	2009-04	19429392
Food-associated estrogenic compounds induce estrogen receptor-mediated luciferase gene expression in transgenic male mice.	2008-07-30	18501883
Aqueous solubility and Daphnia magna chronic toxicity of di(2-ethylhexyl) adipate.	2008-06	18483781
Plastic components affect the activation of the aryl hydrocarbon and the androgen receptor.	2008-04-18	18294747
Measurement of drinking water contaminants by solid phase microextraction initially quantified in source water samples by the USGS.	2008-04-15	18497153
Determination of phthalates and adipate in bottled water by headspace solid-phase microextraction and gas chromatography/mass spectrometry.	2008-01-18	18082753
Plasticizers and their degradation products in the process streams of a large urban physicochemical sewage treatment plant.	2008-01	17706266
Trace phthalate and adipate esters contaminated in packaged food.	2007-06-15	17562465
Effect of surfactants on plasticizer biodegradation by Bacillus subtilis ATCC 6633.	2007-06	17080301
Migration of di(2-ethylhexyl) adipate and acetyltributyl citrate plasticizers from food-grade PVC film into sweetened sesame paste (halawa tehineh): kinetic and penetration study.	2007-04	17141933
Metabolites from the biodegradation of di-ester plasticizers by Rhodococcus rhodochrous.	2006-07-31	16316677
Considerations on ultra-trace analysis of phthalates in drinking water.	2006-07	16797669
Effects of perinatal exposure to phthalate/adipate esters on hypothalamic gene expression and sexual behavior in rats.	2006-06	16493179
Plasticizers in Brazilian food-packaging materials acquired on the retail market.	2006-01	16393819
Dietary exposure to chemical migrants from food contact materials: a probabilistic approach.	2005-10	16236636
A case of contact urticaria due to adigraf, a PVC-made material.	2005-09	21783615
Occurrence of twenty-six endocrine-disrupting compounds in environmental water samples from Catalonia, Spain.	2005-02	15719984
Inhibitory effects of some possible endocrine-disrupting chemicals on the isozymes of human 11beta-hydroxysteroid dehydrogenase and expression of their mRNA in gonads and adrenal glands.	2005	16184081
Temporal variability of urinary phthalate metabolite levels in men of reproductive age.	2004-12	15579421
Early testicular effects in rats perinatally exposed to DEHP in combination with DEHA--apoptosis assessment and immunohistochemical studies.	2004-02-27	15749266
Antiandrogenic effects in male rats perinatally exposed to a mixture of di(2-ethylhexyl) phthalate and di(2-ethylhexyl) adipate.	2004-02-27	15749265
Steroidogenesis in fetal male rats is reduced by DEHP and DINP, but endocrine effects of DEHP are not modulated by DEHA in fetal, prepubertal and adult male rats.	2003-07-01	15013064
Biodegradation of plasticizers by Rhodotorula rubra.	2003-06	12785580
Estrogenic activity of tissue conditioners in vitro.	2003-06	12686300
Estimated daily intake of plasticizers in 1-week duplicate diet samples following regulation of DEHP-containing PVC gloves in Japan.	2003-04	12775472
Di(2-ethylhexyl) adipate (DEHA) induced developmental toxicity but not antiandrogenic effects in pre- and postnatally exposed Wistar rats.	2003-03-19	12642148
[Contents of plasticizers in cap-sealing for bottled food and their migration into food].	2002-12	12635342
Plasticizer contamination from vacuum system O-rings in a quadrupole ion trap mass spectrometer.	2002-08	12216729
Determination of adipate plasticizers in poly(vinyl chloride) by microwave-assisted extraction.	2002-07-19	12187996
Application of on-line solid-phase extraction-gas chromatography-mass spectrometry to the determination of endocrine disruptors in water samples.	2002-07-19	12187982
Preparation of samples for gas chromatography/mass spectrometry analysis of phthalate and adipate esters in plasma and beverages by steam distillation and extraction.	2002-06-27	12083265
[Levels of phthalates and adipates in processed foods and migration of di-isononyl adipate from polyvinyl chloride film into foods].	2002-06	12238159
Biodegradation of plasticizers by Rhodococcus rhodochrous.	2002	12688586
Di(2-ethylhexyl) phthalate contamination of retail packed lunches caused by PVC gloves used in the preparation of foods.	2001-06	11407756
Eleven phthalate esters and di(2-ethylhexyl) adipate in one-week duplicate diet samples obtained from hospitals and their estimated daily intake.	2001-05	11358187
[Contents of eleven phthalates and di(2-ethylhexyl) adipate in retail packed lunches after prohibition of DEHP-containing PVC gloves for cooking purposes].	2001-04	11486379
[Contents of phthalate in polyvinyl chloride toys].	2001-02	11383157

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:36:38 GMT 2025` Edited by `admin` on `Mon Mar 31 18:36:38 GMT 2025`
Record UNII	MBY1SL921L
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CRODAMOL DOA

Preferred Name

English

DIETHYLHEXYL ADIPATE

Official Name

English

BIS(2-ETHYLHEXYL) ADIPATE

Systematic Name

English

NSC-56775

Code

English

ADIPIC ACID DI(2-ETHYLHEXYL) ESTER

Systematic Name

English

DI(2-ETHYLHEXYL) ADIPATE

Systematic Name

English

DOA

Common Name

English

DI-(2-ETHYLHEXYL)ADIPATE [MART.]

Common Name

English

BIS(2-ETHYLHEXYL)HEXANEDIOATE [HSDB]

Common Name

English

HEXANEDIOIC ACID, 1,6-BIS(2-ETHYLHEXYL) ESTER

Common Name

English

DI(2-ETHYLHEXYL) ADIPATE [IARC]

Common Name

English

DEHA

Common Name

English

Code System Code Type Description

CAS

103-23-1