MAZDUTIDE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 04:42:33 GMT 2025` Edited by `admin` on `Wed Apr 02 04:42:33 GMT 2025`
Protein Type	PEPTIDE
Protein Sub Type	GLUCAGON-LIKE PEPTIDE
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	MB76Z4IBZ5
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

IBI362

Preferred Name

English

MAZDUTIDE

Official Name

English

mazdutide [INN]

Common Name

English

IBI-362

Common Name

English

GLYCINAMIDE, L-HISTIDYL-2-METHYLALANYL-L-GLUTAMINYLGLYCYL-L-THREONYL-L-PHENYLALANYL-L-THREONYL-L-SERYL-L-.ALPHA.-ASPARTYL-L-TYROSYL-L-SERYL-L-LYSYL-L-TYROSYL-L-LEUCYL-L-.ALPHA.-ASPARTYL-L-.ALPHA.-GLUTAMYL-L-LYSYL-L-LYSYL-L-ALANYL-N6-(N-(19-CARBOXY-1-OXON

Systematic Name

English

LY-3305677

Code

English

MAZDUTIDE [USAN]

Common Name

English

LY3305677

Code

English

L-HISTIDYL-2-METHYLALANYL-L-GLUTAMINYLGLYCYL-L-THREONYL-L-PHENYLALANYL-L-THREONYL-L-SERYL-L-.ALPHA.-ASPARTYL-L-TYROSYL-L-SERYL-L-LYSYL-L-TYROSYL-L-LEUCYL-L-.ALPHA.-ASPARTYL-L-.ALPHA.-GLUTAMYL-L-LYSYL-L-LYSYL-L-ALANYL-N6-((2-(2-((N-.ALPHA.-(19-CARBOXYNONA

Systematic Name

English

Code System Code Type Description

FDA UNII

MB76Z4IBZ5

Created by admin on Wed Apr 02 04:42:33 GMT 2025 , Edited by admin on Wed Apr 02 04:42:33 GMT 2025

PRIMARY

NCI_THESAURUS

C186406

Created by admin on Wed Apr 02 04:42:33 GMT 2025 , Edited by admin on Wed Apr 02 04:42:33 GMT 2025

PRIMARY

INN

12034

Created by admin on Wed Apr 02 04:42:33 GMT 2025 , Edited by admin on Wed Apr 02 04:42:33 GMT 2025

PRIMARY

SMS_ID

300000039985

Created by admin on Wed Apr 02 04:42:33 GMT 2025 , Edited by admin on Wed Apr 02 04:42:33 GMT 2025

PRIMARY

USAN

JK-37

Created by admin on Wed Apr 02 04:42:33 GMT 2025 , Edited by admin on Wed Apr 02 04:42:33 GMT 2025

PRIMARY

CAS

2259884-03-0

Created by admin on Wed Apr 02 04:42:33 GMT 2025 , Edited by admin on Wed Apr 02 04:42:33 GMT 2025

PRIMARY

Related Record Type Details


					G2BWF9H576

GLUCAGON RECEPTOR

TARGET -> AGONIST

Amount:


					EF38T7N5MI

GLUCAGON-LIKE PEPTIDE 1 RECEPTOR

TARGET -> AGONIST

Amount:

Related Record Type Details


					MB76Z4IBZ5

MAZDUTIDE

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_34]	C-TERMINUS			GLYCINAMIDE	4JDT453NWO
AMINO_ACID_SUBSTITUTION	[1_20]	SITE_SPECIFIC			N6-(N-(HYDROGEN ICOSANEDIOYL)-.GAMMA.-GLU-BIS(IMINOBIS(ETHYLENOXY)ACETYL))-LYSINE	NVV1P9GCY2
AMINO_ACID_SUBSTITUTION	[1_2]	SITE_SPECIFIC			.ALPHA.-AMINOISOBUTYRIC ACID	1E7ZW41IQU

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL