NAFETOLOL

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C19H29NO3
Molecular Weight	319.4385
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of NAFETOLOL

Structure Search

SMILES

CC(C)(C)NCC(O)COC1=CC=C(O)C2=C1C3CCC2CC3

InChI

InChIKey=GEVXLKYQQIKELK-UHFFFAOYSA-N

InChI=1S/C19H29NO3/c1-19(2,3)20-10-14(21)11-23-16-9-8-15(22)17-12-4-6-13(7-5-12)18(16)17/h8-9,12-14,20-22H,4-7,10-11H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C19H29NO3
Molecular Weight	319.4385
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6104601 | https://shodhganga.inflibnet.ac.in/bitstream/10603/101297/13/13_chapter%204.pdf

Nafetolol (K5407) is a beta-blocking agent.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Pharmacokinetics and metabolism of a new beta-adrenergic blocking agent, the 1, ter-butyl-amino-3-(1,2,3,4-tetrahydro-1,4-ethano-8-hydroxy-5-naphthoxy)-2-propanol (K 5407).	1980	6104601

Patents

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Other

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:10:15 GMT 2023` Edited by `admin` on `Fri Dec 15 16:10:15 GMT 2023`
Record UNII	MAL2XF17MP
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

NAFETOLOL

Official Name

English

nafetolol [INN]

Common Name

English

1-(TERT-BUTYLAMINO)-3-((1,2,3,4-TETRAHYDRO-8-HYDROXY-1,4-ETHANONAPHTHALEN-5-YL)OXY)-2-PROPANOL

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29576

Created by admin on Fri Dec 15 16:10:15 GMT 2023 , Edited by admin on Fri Dec 15 16:10:15 GMT 2023

Code System Code Type Description

FDA UNII

MAL2XF17MP

Created by admin on Fri Dec 15 16:10:15 GMT 2023 , Edited by admin on Fri Dec 15 16:10:15 GMT 2023

PRIMARY

EPA CompTox

DTXSID90866071

Created by admin on Fri Dec 15 16:10:15 GMT 2023 , Edited by admin on Fri Dec 15 16:10:15 GMT 2023

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INN

4396

Created by admin on Fri Dec 15 16:10:15 GMT 2023 , Edited by admin on Fri Dec 15 16:10:15 GMT 2023

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PUBCHEM

68668

Created by admin on Fri Dec 15 16:10:15 GMT 2023 , Edited by admin on Fri Dec 15 16:10:15 GMT 2023

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NCI_THESAURUS

C90799

Created by admin on Fri Dec 15 16:10:15 GMT 2023 , Edited by admin on Fri Dec 15 16:10:15 GMT 2023

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ChEMBL

CHEMBL1742445

Created by admin on Fri Dec 15 16:10:15 GMT 2023 , Edited by admin on Fri Dec 15 16:10:15 GMT 2023

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EVMPD

SUB09121MIG

Created by admin on Fri Dec 15 16:10:15 GMT 2023 , Edited by admin on Fri Dec 15 16:10:15 GMT 2023

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SMS_ID

100000084433

Created by admin on Fri Dec 15 16:10:15 GMT 2023 , Edited by admin on Fri Dec 15 16:10:15 GMT 2023

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CAS

42050-23-7

Created by admin on Fri Dec 15 16:10:15 GMT 2023 , Edited by admin on Fri Dec 15 16:10:15 GMT 2023

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Related Record Type Details


					MAL2XF17MP

NAFETOLOL

ACTIVE MOIETY