Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Wed Apr 02 07:15:47 GMT 2025
by
admin
on
Wed Apr 02 07:15:47 GMT 2025
|
| Protein Type | PEPTIDE |
| Protein Sub Type | |
| Sequence Origin | HUMAN |
| Sequence Type | COMPLETE |
| Record UNII |
MA5AQ51HF3
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| Record Status |
Validated (UNII)
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| Record Version |
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-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
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Preferred Name | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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MA5AQ51HF3
Created by
admin on Wed Apr 02 07:15:47 GMT 2025 , Edited by admin on Wed Apr 02 07:15:47 GMT 2025
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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INHIBITOR OF AGGREGATION->TARGET |
A?pE is of interest as it has been shown to be one of the dominant forms of A? present in the hippocampi and cortices of patients with Alzheimer's disease. However, arguably of most importance is that A?pE is specifically only found within cerebral A? plaques.2 In-vitro analysis has revealed that A?pE3 shows an increased rate of aggregation up to 250 times that of full-length A?, irrespective of its C terminus.
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INHIBITOR OF EXPRESSION->TARGET |
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Structural Modifications
| Modification Type | Location Site | Location Type | Residue Modified | Extent | Fragment Name | Fragment Approval |
|---|---|---|---|---|---|---|
| AMINO_ACID_SUBSTITUTION | [1_1] | PIDOLIC ACID | SZB83O1W42 |
| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
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