BARECETAMAB

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 16:11:40 GMT 2023` Edited by `admin` on `Sat Dec 16 16:11:40 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	M9SE4M9U1V
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BARECETAMAB

Official Name

English

IMMUNOGLOBULIN G1-LAMBDA, ANTI-(HOMO SAPIENS ERBB3 (RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3, HER3)), HOMO SAPIENS MONOCLONAL ANTIBODY; GAMMA1 HEAVY CHAIN HOMO SAPIENS (1-451) (VH (HOMO SAPIENS IGHV3-23*01 (90.8%)-(IGHD)-IGHJ4*01 (100%)) CDR-IMGT (8.8.14)

Common Name

English

Barecetamab [WHO-DD]

Common Name

English

ISU104

Code

English

barecetamab [INN]

Common Name

English

ISU-104

Code

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR HER3) (HUMAN MONOCLONAL ISU104 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL ISU104 .LAMBDA.-CHAIN, DIMER

Common Name

English

Code System Code Type Description

NCI_THESAURUS

C158746

Created by admin on Sat Dec 16 16:11:40 GMT 2023 , Edited by admin on Sat Dec 16 16:11:40 GMT 2023

PRIMARY

INN

11386

Created by admin on Sat Dec 16 16:11:40 GMT 2023 , Edited by admin on Sat Dec 16 16:11:40 GMT 2023

PRIMARY

FDA UNII

M9SE4M9U1V

Created by admin on Sat Dec 16 16:11:40 GMT 2023 , Edited by admin on Sat Dec 16 16:11:40 GMT 2023

PRIMARY

CAS

2275727-74-5

Created by admin on Sat Dec 16 16:11:40 GMT 2023 , Edited by admin on Sat Dec 16 16:11:40 GMT 2023

PRIMARY

From	To
4_138	4_197
4_22	4_89
3_138	3_197
3_22	3_89
2_371	2_429
2_265	2_325
2_224	4_215
2_148	2_204
2_22	2_96
1_371	1_429
1_265	1_325
1_233	2_233
1_230	2_230
1_224	3_215
1_148	1_204
1_22	1_96

Glycosylation Link Type	Site
N	1_301
N	2_301

Related Record Type Details


					RSO83C9PIA

RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3

TARGET -> INHIBITOR

Comments:

ISU104 completely suppressed Heregulin HRG-induced phosphorylation

Amount:

Related Record Type Details


					M9SE4M9U1V

BARECETAMAB

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL