Velmanase Alfa

Approval Year

Substance Class	Protein
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	M91TG242P2
Record Status	`Validated (UNII)`
Record Version

Related Record	Type
No data available in table

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Name

Type

Language

Velmanase Alfa

Official Name

English

LAMAZYM

Preferred Name

English

MANNOSIDASE, ALPHA, CLASS 2B, MEMBER 1, RECOMBINANT

Common Name

English

VELMANASE ALFA [USAN]

Common Name

English

CHFLMZYMAA1

Code

English

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Classification Tree

Code System

Code

Designated/Approved

FDA ORPHAN DRUG

212005

Biological Agent

NCI_THESAURUS

C29726

Enzymes

WHO-ATC

A16AB15

Positive

EU-Orphan Drug

EU/3/04/260

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Code System

Code

Type

Description

FDA UNII

M91TG242P2

PRIMARY

NCI_THESAURUS

C152849

PRIMARY

CAS

9025-42-7

GENERIC (FAMILY)

WIKIPEDIA

Velmanase alfa

PRIMARY

EVMPD

SUB180967

PRIMARY

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Subunit 0

Subunit 1

Subunit 2

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From	To
1_6	1_309
1_219	1_224
1_363	1_423
1_444	1_452

Showing 1 to 4 of 4 entries

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Linkage Type	Residue Index
COORDINATION COMPOUND	1_23	1_25	1_147	1_397

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_84
N	1_261
N	1_318
N	1_448
N	2_43
N	2_49
N	2_90
N	2_164
N	2_230
N	3_58
N	3_107

Related Record Type Details

Velmanase Alfa-TYCV

SUB_CONCEPT->SUBSTANCE

Amount:

Related Record Type Details


					M91TG242P2

Velmanase Alfa

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_23] [1_25] [1_147] [1_397]	SITE_SPECIFIC			UNSPECIFIED SUBSTANCE	622ec997 (not in database)

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL	ESTIMATED C4883H7434N1366O1408S28
MOL_WEIGHT:GEL FILTRATION	CHEMICAL	GEL FILTRATION 205000 DA (average)