Stereochemistry | ACHIRAL |
Molecular Formula | C19H18O7 |
Molecular Weight | 358.342 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC2=C(C(=O)C(OC)=C(O2)C3=CC(OC)=C(OC)C=C3)C(O)=C1
InChI
InChIKey=HHGPYJLEJGNWJA-UHFFFAOYSA-N
InChI=1S/C19H18O7/c1-22-11-8-12(20)16-15(9-11)26-18(19(25-4)17(16)21)10-5-6-13(23-2)14(7-10)24-3/h5-9,20H,1-4H3
Molecular Formula | C19H18O7 |
Molecular Weight | 358.342 |
Charge | 0 |
Count |
MOL RATIO
1 MOL RATIO (average) |
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Retusin is an O-methylated isoflavone, a type of flavonoid. It can be found in Fabaceae species like Dipteryx odorata, in Dalbergia retusa and in Millettia nitida. Retusin exhibited potent free-radical-scavenging capacity as well as efficient inhibition of cellular melanogenesis, suggesting that it is a valuable hit compound with potential for advanced cosmeceutical development. Retusin showed efficient inhibition both of cellular melanin formation and anti-tyrosinase activity in B16F10 melanocytes. Retusin exhibited an anti-emetic effect in chick model.