2?,4?-Dihydroxychalcone

Details

Stereochemistry	ACHIRAL
Molecular Formula	C15H12O3
Molecular Weight	240.254
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC1=CC=C(C(=O)\C=C\C2=CC=CC=C2)C(O)=C1

InChI

InChIKey=JUMSUVHHUVPSOY-RMKNXTFCSA-N

InChI=1S/C15H12O3/c16-12-7-8-13(15(18)10-12)14(17)9-6-11-4-2-1-3-5-11/h1-10,16,18H/b9-6+

HIDE SMILES / InChI

Molecular Formula	C15H12O3
Molecular Weight	240.254
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Heat shock protein HSP 90-alpha 12 Target ID: P07900 Gene ID: 3320.0 Gene Symbol: HSP90AA1 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/26190922	Inhibitor 8504

PubMed

Title	Date	PubMed
In Vitro Antifungal Activity and Mode of Action of 2',4'-Dihydroxychalcone against Aspergillus fumigatus.	2015-06	26190922

Substance Class	Chemical Created by `admin` on `Tue Apr 01 20:11:22 GMT 2025` Edited by `admin` on `Tue Apr 01 20:11:22 GMT 2025`
Record UNII	M7LF69Z68L
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

NSC-401492

Preferred Name

English

2?,4?-Dihydroxychalcone

Common Name

English

trans-2?,4?-Dihydroxychalcone

Common Name

English

(E)-1-(2,4-Dihydroxyphenyl)-3-phenylprop-2-en-1-one

Systematic Name

English

CHALCONE, 2',4'-DIHYDROXY-

Systematic Name

English

1-(2,4-Dihydroxyphenyl)-3-phenyl-2-propen-1-one

Systematic Name

English

2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-phenyl-

Systematic Name

English

2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-phenyl-, (2E)

Systematic Name

English

Code System Code Type Description

CAS

25515-43-9