Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C16H29N3O6S |
| Molecular Weight | 391.483 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCCCSC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O
InChI
InChIKey=HXJDWCWJDCOHDG-RYUDHWBXSA-N
InChI=1S/C16H29N3O6S/c1-2-3-4-5-8-26-10-12(15(23)18-9-14(21)22)19-13(20)7-6-11(17)16(24)25/h11-12H,2-10,17H2,1H3,(H,18,23)(H,19,20)(H,21,22)(H,24,25)/t11-,12-/m0/s1
| Molecular Formula | C16H29N3O6S |
| Molecular Weight | 391.483 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Role of gamma-glutamyl transpeptidase in redox regulation of K+ channel remodeling in postmyocardial infarction rat hearts. | 2009-08 |
|
| Modulating catalytic activity by unnatural amino acid residues in a GSH-binding loop of GST P1-1. | 2008-02-22 |
|
| Probing the mechanism of GSH activation in Schistosoma haematobium glutathione-S-transferase by site-directed mutagenesis and X-ray crystallography. | 2006-07-14 |
|
| Nitric oxide-mediated effect of nipradilol, an alpha- and beta-adrenergic blocker, on glutamate neurotoxicity in rat cortical cultures. | 2006-03-27 |
|
| Plasmodium falciparum glutathione S-transferase--structural and mechanistic studies on ligand binding and enzyme inhibition. | 2006-02 |
|
| Structural basis of the suppressed catalytic activity of wild-type human glutathione transferase T1-1 compared to its W234R mutant. | 2006-01-06 |
|
| Tertiary interactions stabilise the C-terminal region of human glutathione transferase A1-1: a crystallographic and calorimetric study. | 2005-06-17 |
|
| Structure of the major cytosolic glutathione S-transferase from the parasitic nematode Onchocerca volvulus. | 2005-04-01 |
|
| Crystallographic and thermodynamic analysis of the binding of S-octylglutathione to the Tyr 7 to Phe mutant of glutathione S-transferase from Schistosoma japonicum. | 2005-02-01 |
|
| Native and inhibited structure of a Mu class-related glutathione S-transferase from Plasmodium falciparum. | 2004-01-09 |
|
| Structure of an insect delta-class glutathione S-transferase from a DDT-resistant strain of the malaria vector Anopheles gambiae. | 2003-12 |
|
| Thermodynamic description of the effect of the mutation Y49F on human glutathione transferase P1-1 in binding with glutathione and the inhibitor S-hexylglutathione. | 2003-11-21 |
|
| The anomalous pKa of Tyr-9 in glutathione S-transferase A1-1 catalyzes product release. | 2003-05-23 |
|
| Characterization of the electrophile binding site and substrate binding mode of the 26-kDa glutathione S-transferase from Schistosoma japonicum. | 2003-04-01 |
|
| 1.3-A resolution structure of human glutathione S-transferase with S-hexyl glutathione bound reveals possible extended ligandin binding site. | 2002-09-01 |
|
| Role of GST P1-1 in mediating the effect of etoposide on human neuroblastoma cell line Sh-Sy5y. | 2002 |
|
| Crystal structures of the yeast prion Ure2p functional region in complex with glutathione and related compounds. | 2001-11-13 |
|
| Purification and characterization of a glutathione S-transferase Omega in pig: evidence for two distinct organ-specific transcripts. | 2001-08-15 |
|
| Functional residues on the enzyme active site of glyoxalase I from bovine brain. | 2001-08 |
|
| An alternative pathway for metabolism of leukotriene D(4): effects on contractions to cysteinyl-leukotrienes in the guinea-pig trachea. | 2001-08 |
|
| 3-Methyleneoxindole: an affinity label of glutathione S-transferase pi which targets tryptophan 38. | 2001-06-26 |
|
| Ligand-induced changes in the structure and dynamics of a human class Mu glutathione S-transferase. | 2000-06-27 |
|
| The three-dimensional structure of an avian class-mu glutathione S-transferase, cGSTM1-1 at 1.94 A resolution. | 1998-04-24 |
|
| Interaction of glutathione transferase P1-1 with captan and captafol. | 1996-07-12 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:02:00 GMT 2025
by
admin
on
Mon Mar 31 19:02:00 GMT 2025
|
| Record UNII |
M73SNN908F
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
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