Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C4H6O3 |
| Molecular Weight | 102.0886 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)CCC=O
InChI
InChIKey=UIUJIQZEACWQSV-UHFFFAOYSA-N
InChI=1S/C4H6O3/c5-3-1-2-4(6)7/h3H,1-2H2,(H,6,7)
| Molecular Formula | C4H6O3 |
| Molecular Weight | 102.0886 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Pharmacologic rescue of lethal seizures in mice deficient in succinate semialdehyde dehydrogenase. | 2001 Oct |
|
| Selective involvement of the globus pallidus and dentate nucleus in succinic semialdehyde dehydrogenase deficiency. | 2002 Aug |
|
| Evidence that gamma-aminobutyric acid is a major nitrogen source during Cladosporium fulvum infection of tomato. | 2002 Jan |
|
| GabR, a member of a novel protein family, regulates the utilization of gamma-aminobutyrate in Bacillus subtilis. | 2002 Jul |
|
| Prenatal diagnosis of succinate semialdehyde dehydrogenase deficiency in non-identical twins. | 2002 Oct |
|
| Phytol, SSADH inhibitory diterpenoid of Lactuca sativa. | 2002 Oct |
|
| Murine succinate semialdehyde dehydrogenase deficiency. | 2003 |
|
| GABA, gamma-hydroxybutyric acid, and neurological disease. | 2003 |
|
| Cloning and characterization of a gene cluster involved in tetrahydrofuran degradation in Pseudonocardia sp. strain K1. | 2003 Apr |
|
| The altered expression of GABA shunt enzymes in the gerbil hippocampus before and after seizure generation. | 2003 Feb |
|
| A novel gamma-hydroxybutyrate dehydrogenase: identification and expression of an Arabidopsis cDNA and potential role under oxygen deficiency. | 2003 Oct 17 |
|
| Succinic semialdehyde dehydrogenase deficiency (SSADH) (4-hydroxybutyric aciduria, gamma-hydroxybutyric aciduria). | 2004 |
|
| Clinical aspects of the disorders of GABA metabolism in children. | 2004 Apr |
|
| The ALDH gene superfamily of Arabidopsis. | 2004 Aug |
|
| Seizure evolution and amino acid imbalances in murine succinate semialdehyde dehydrogenase (SSADH) deficiency. | 2004 Aug |
|
| Emerging experimental therapeutics for bipolar disorder: insights from the molecular and cellular actions of current mood stabilizers. | 2004 Aug |
|
| Photosensitive absence epilepsy with myoclonias and heterozygosity for succinic semialdehyde dehydrogenase (SSADH) deficiency. | 2004 Jun |
|
| Effect of genetically caused excess of brain gamma-hydroxybutyric acid and GABA on sleep. | 2005 Apr |
|
| High-level expression and characterization of the recombinant enzyme, and tissue distribution of human succinic semialdehyde dehydrogenase. | 2005 Nov |
|
| Succinic semialdehyde dehydrogenase (SSADH) deficiency: Molecular analysis in a South American family. | 2006 Aug |
|
| Inhibition of GABA shunt enzymes' activity by 4-hydroxybenzaldehyde derivatives. | 2006 Feb |
|
| Succinic semialdehyde dehydrogenase deficiency: GABAB receptor-mediated function. | 2006 May 23 |
|
| Oxo-4-methylpentanoic acid directs the metabolism of GABA into the Krebs cycle in rat pancreatic islets. | 2006 Nov 15 |
|
| Succinic semialdehyde couples stress response to quorum-sensing signal decay in Agrobacterium tumefaciens. | 2006 Oct |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 19:46:57 UTC 2023
by
admin
on
Fri Dec 15 19:46:57 UTC 2023
|
| Record UNII |
M73BX3CPMU
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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SUCCINIC SEMIALDEHYDE
Created by
admin on Fri Dec 15 19:46:57 UTC 2023 , Edited by admin on Fri Dec 15 19:46:57 UTC 2023
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DTXSID00219231
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admin on Fri Dec 15 19:46:57 UTC 2023 , Edited by admin on Fri Dec 15 19:46:57 UTC 2023
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16265
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M73BX3CPMU
Created by
admin on Fri Dec 15 19:46:57 UTC 2023 , Edited by admin on Fri Dec 15 19:46:57 UTC 2023
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1112
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692-29-5
Created by
admin on Fri Dec 15 19:46:57 UTC 2023 , Edited by admin on Fri Dec 15 19:46:57 UTC 2023
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| Related Record | Type | Details | ||
|---|---|---|---|---|
|
PARENT -> METABOLITE |
nitiated by the action of GHB dehydrogenase
|
