U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
This repository is under review for potential modification in compliance with Administration directives.

Approval Year

Substance Class Protein
Created
by admin
on Wed Apr 02 17:21:58 GMT 2025
Edited
by admin
on Wed Apr 02 17:21:58 GMT 2025
Protein Type ENZYME
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
M6V3XDT957
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
6-O-methylguanine-DNA methyltransferase
Common Name English
MGMT
Preferred Name English
O-6-methylguanine-DNA-alkyltransferase
Common Name English
Methylated-DNA--protein-cysteine methyltransferase
Common Name English
Code System Code Type Description
FDA UNII
M6V3XDT957
Created by admin on Wed Apr 02 17:21:58 GMT 2025 , Edited by admin on Wed Apr 02 17:21:58 GMT 2025
PRIMARY
UNIPROT
P16455
Created by admin on Wed Apr 02 17:21:58 GMT 2025 , Edited by admin on Wed Apr 02 17:21:58 GMT 2025
PRIMARY
Related Record Type Details
INHIBITOR -> TARGET

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
AMINO_ACID_SUBSTITUTION [1_14] [1_201] SITE_SPECIFIC S DEXFOSFOSERINE VI4F0K069V
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL