VIBAPAPOGENE AUTOLEUCEL

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Sat Dec 16 18:57:05 UTC 2023` Edited by `admin` on `Sat Dec 16 18:57:05 UTC 2023`
Source Materials Class	ORGANISM
Source Materials Type	ALLOGENIC HUMAN
Source Materials State	LIVE GENETICALLY MODIFIED
Source Materials Parent	`G0T704E6Z3` HOMO SAPIENS WHOLE
Part	BLOOD
Fraction Material Type	CELL
Fraction Name	PBMCs
Record UNII	M6CQK5YE94
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

VIBAPAPOGENE AUTOLEUCEL

Official Name

English

vibapapogene autoleucel [INN]

Common Name

English

AUTOLOGOUS PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMCS), SPECIFICALLY B LYMPHOCYTES AND MONOCYTES THAT ARE T-CELL DEPLETED, TRANSFECTED EX VIVO WITH A NON-REPLICATING ADENOVIRAL VECTOR THAT EXPRESSES A CODON-OPTIMISED FUSION OF TUMOUR-ASSOCIATED ANTIGENS (

Common Name

English

AUTOLOGOUS PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMCS) EXPRESSING HUMAN PAPILLOMAVIRUS TYPES 16 & 18 ANTIGENS

Common Name

English

Code System Code Type Description

INN

11403

Created by admin on Sat Dec 16 18:57:05 UTC 2023 , Edited by admin on Sat Dec 16 18:57:05 UTC 2023

PRIMARY

FDA UNII

M6CQK5YE94

Created by admin on Sat Dec 16 18:57:05 UTC 2023 , Edited by admin on Sat Dec 16 18:57:05 UTC 2023

PRIMARY

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HUMAN PAPILLOMAVIRUS SEROTYPE 18 WHOLE

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HUMAN PAPILLOMAVIRUS SEROTYPE 16 WHOLE

TARGET ORGANISM->VACCINE ANTIGEN

Amount:

Related Record Type Details


					M6CQK5YE94

VIBAPAPOGENE AUTOLEUCEL

ACTIVE MOIETY

Amount:

Agent Modifications

Modification Process	Modification Role	Modification Type	Amount	Fragment Name	Fragment ID
ADENOVIRUS TRANSFECTION	TRANSFECTION	BIOLOGICAL		VIBAPAPOGENE AUTOLEUCEL ADENOVIRUS VECTOR	5UQP3U7K79

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
GENE_EXPRESSION VECTOR					VIBAPAPOGENE AUTOLEUCEL ADENOVIRUS VECTOR GENOME	LU44VB4DV5