TECLOTHIAZIDE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C8H7Cl4N3O4S2
Molecular Weight	415.101
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TECLOTHIAZIDE

Structure Search

SMILES

NS(=O)(=O)C1=C(Cl)C=C2NC(NS(=O)(=O)C2=C1)C(Cl)(Cl)Cl

InChI

InChIKey=GUTZRTRUIMWMJZ-UHFFFAOYSA-N

InChI=1S/C8H7Cl4N3O4S2/c9-3-1-4-6(2-5(3)20(13,16)17)21(18,19)15-7(14-4)8(10,11)12/h1-2,7,14-15H,(H2,13,16,17)

HIDE SMILES / InChI

Molecular Formula	C8H7Cl4N3O4S2
Molecular Weight	415.101
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/20199 | Milne George W.A., Drugs: Synonyms and Properties: Synonyms and Properties, retrieved from: https://books.google.ru/books?id=xUlaDwAAQBAJ&pg=PT1372&lpg=PT1372&dq=PS-207+TECLOTHIAZIDE&source=bl&ots=CnAXkPhwjO&sig=ACfU3U2CC1Q5HJkJdi5WlWR7T8hykg2Eqw&hl=ru&sa=X&ved=2ahUKEwjpjPCtmaHjAhUmtYsKHXVWBnMQ6AEwDHoECAgQAQ#v=onepage&q=PS-207%20TECLOTHIAZIDE&f=false

Teclothiazide is a thiazide diuretic that has never been marketed. Information about the current use of this drug is not available.

Approval Year

PubMed

PubMed

Title	Date	PubMed
[Effects of a beta-adrenolytic and a diuretic vis-à-vis hyper-reninemia induced by isoprenaline in anesthetized dogs. Value of beta blocking-diuretic interaction].	1977	20199

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:11:16 GMT 2023` Edited by `admin` on `Fri Dec 15 16:11:16 GMT 2023`
Record UNII	M69O7IV78O
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TECLOTHIAZIDE

Official Name

English

6-CHLORO-3,4-DIHYDRO-3-(TRICHLOROMETHYL)-2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE 1,1-DIOXIDE

Systematic Name

English

TECLOTHIAZIDE [MI]

Common Name

English

teclothiazide [INN]

Common Name

English

Teclothiazide [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C49185

Created by admin on Fri Dec 15 16:11:16 GMT 2023 , Edited by admin on Fri Dec 15 16:11:16 GMT 2023

Code System Code Type Description

EVMPD

SUB10862MIG

Created by admin on Fri Dec 15 16:11:16 GMT 2023 , Edited by admin on Fri Dec 15 16:11:16 GMT 2023

PRIMARY

INN

1262

Created by admin on Fri Dec 15 16:11:16 GMT 2023 , Edited by admin on Fri Dec 15 16:11:16 GMT 2023

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ECHA (EC/EINECS)

224-253-3

Created by admin on Fri Dec 15 16:11:16 GMT 2023 , Edited by admin on Fri Dec 15 16:11:16 GMT 2023

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SMS_ID

100000082437

Created by admin on Fri Dec 15 16:11:16 GMT 2023 , Edited by admin on Fri Dec 15 16:11:16 GMT 2023

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MESH

C015526

Created by admin on Fri Dec 15 16:11:16 GMT 2023 , Edited by admin on Fri Dec 15 16:11:16 GMT 2023

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FDA UNII

M69O7IV78O

Created by admin on Fri Dec 15 16:11:16 GMT 2023 , Edited by admin on Fri Dec 15 16:11:16 GMT 2023

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DRUG CENTRAL

2575

Created by admin on Fri Dec 15 16:11:16 GMT 2023 , Edited by admin on Fri Dec 15 16:11:16 GMT 2023

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ChEMBL

CHEMBL2105516

Created by admin on Fri Dec 15 16:11:16 GMT 2023 , Edited by admin on Fri Dec 15 16:11:16 GMT 2023

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PUBCHEM

71656

Created by admin on Fri Dec 15 16:11:16 GMT 2023 , Edited by admin on Fri Dec 15 16:11:16 GMT 2023

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EPA CompTox

DTXSID40102163

Created by admin on Fri Dec 15 16:11:16 GMT 2023 , Edited by admin on Fri Dec 15 16:11:16 GMT 2023

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MERCK INDEX

m10511

Created by admin on Fri Dec 15 16:11:16 GMT 2023 , Edited by admin on Fri Dec 15 16:11:16 GMT 2023

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Merck Index

NCI_THESAURUS

C77019

Created by admin on Fri Dec 15 16:11:16 GMT 2023 , Edited by admin on Fri Dec 15 16:11:16 GMT 2023

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CAS

4267-05-4

Created by admin on Fri Dec 15 16:11:16 GMT 2023 , Edited by admin on Fri Dec 15 16:11:16 GMT 2023

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TECLOTHIAZIDE POTASSIUM

SALT/SOLVATE -> PARENT

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					M69O7IV78O

ACTIVE MOIETY