U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 15:24:06 GMT 2023
Edited
by admin
on Sat Dec 16 15:24:06 GMT 2023
Protein Type stimulating factor
Protein Sub Type
Sequence Type COMPLETE
Record UNII
M65IE9C8XJ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PROTEOGLYCAN 4
Common Name English
LUBRICIN
Common Name English
SUPERFICIAL ZONE PROTEOGLYCAN
Common Name English
PROTEOGLYCAN 4 (HUMAN)
Common Name English
MEGAKARYOCYTE-STIMULATING FACTOR
Common Name English
Code System Code Type Description
DAILYMED
M65IE9C8XJ
Created by admin on Sat Dec 16 15:24:06 GMT 2023 , Edited by admin on Sat Dec 16 15:24:06 GMT 2023
PRIMARY
FDA UNII
M65IE9C8XJ
Created by admin on Sat Dec 16 15:24:06 GMT 2023 , Edited by admin on Sat Dec 16 15:24:06 GMT 2023
PRIMARY
RXCUI
2619327
Created by admin on Sat Dec 16 15:24:06 GMT 2023 , Edited by admin on Sat Dec 16 15:24:06 GMT 2023
PRIMARY
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_182
N 1_1135
N 2_182
N 2_1135
O 1_99
O 1_112
O 1_216
O 1_229
O 1_253
O 1_267
O 1_281
O 1_282
O 1_286
O 1_293
O 1_300
O 1_308
O 1_314
O 1_343
O 1_349
O 1_352
O 1_360
O 1_361
O 1_364
O 1_367
O 1_375
O 1_376
O 1_383
O 1_384
O 1_391
O 1_399
O 1_403
O 1_406
O 1_414
O 1_415
O 1_422
O 1_423
O 1_430
O 1_431
O 1_453
O 1_454
O 1_461
O 1_469
O 1_470
O 1_477
O 1_478
O 1_485
O 1_501
O 1_505
O 1_508
O 1_516
O 1_517
O 1_529
O 1_531
O 1_539
O 1_540
O 1_547
O 1_548
O 1_555
O 1_556
O 1_563
O 1_564
O 1_571
O 1_579
O 1_580
O 1_587
O 1_588
O 1_592
O 1_595
O 1_603
O 1_652
O 1_659
O 1_660
O 1_667
O 1_668
O 1_675
O 1_676
O 1_680
O 1_683
O 1_699
O 1_700
O 1_712
O 1_744
O 1_745
O 1_752
O 1_753
O 1_768
O 1_769
O 1_781
O 1_788
O 1_805
O 1_813
O 1_814
O 1_868
O 1_876
O 1_906
O 1_907
O 1_938
O 1_939
O 1_944
O 1_951
O 1_954
O 1_955
O 1_956
O 1_1015
O 1_1137
O 2_99
O 2_112
O 2_216
O 2_229
O 2_253
O 2_267
O 2_281
O 2_282
O 2_286
O 2_293
O 2_300
O 2_308
O 2_314
O 2_343
O 2_349
O 2_352
O 2_360
O 2_361
O 2_364
O 2_367
O 2_375
O 2_376
O 2_383
O 2_384
O 2_391
O 2_399
O 2_403
O 2_406
O 2_414
O 2_415
O 2_422
O 2_423
O 2_430
O 2_431
O 2_453
O 2_454
O 2_461
O 2_469
O 2_470
O 2_477
O 2_478
O 2_485
O 2_501
O 2_505
O 2_508
O 2_516
O 2_517
O 2_529
O 2_531
O 2_539
O 2_540
O 2_547
O 2_548
O 2_555
O 2_556
O 2_563
O 2_564
O 2_571
O 2_579
O 2_580
O 2_587
O 2_588
O 2_592
O 2_595
O 2_603
O 2_652
O 2_659
O 2_660
O 2_667
O 2_668
O 2_675
O 2_676
O 2_680
O 2_683
O 2_699
O 2_700
O 2_712
O 2_744
O 2_745
O 2_752
O 2_753
O 2_768
O 2_769
O 2_781
O 2_788
O 2_805
O 2_813
O 2_814
O 2_868
O 2_876
O 2_906
O 2_907
O 2_938
O 2_939
O 2_944
O 2_951
O 2_954
O 2_955
O 2_956
O 2_1015
O 2_1137
Related Record Type Details
ACTIVATOR OF EXPRESSION->TARGET
Increased expression of PRG4 mRNA in tendons treated with rabPXL01 in HA, but not in tendon sheaths. In addition, treatment with rabPXL01 in HA led to repression of the mRNA levels for the pro-inflammatory mediators interleukin (IL)-1β, IL-6, and IL-8 in tendon sheaths.
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL