AMOLANONE HYDROCHLORIDE

First approved in 1941

Details

Stereochemistry	RACEMIC
Molecular Formula	C20H23NO2.ClH
Molecular Weight	345.863
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CCN(CC)CCC1(C(=O)OC2=C1C=CC=C2)C3=CC=CC=C3

InChI

InChIKey=JLTVLLBWSZPXFN-UHFFFAOYSA-N

InChI=1S/C20H23NO2.ClH/c1-3-21(4-2)15-14-20(16-10-6-5-7-11-16)17-12-8-9-13-18(17)23-19(20)22;/h5-13H,3-4,14-15H2,1-2H3;1H

HIDE SMILES / InChI

Molecular Formula	C20H23NO2
Molecular Weight	309.4021
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13496207 | https://www.drugfuture.com/chemdata/amolanone.html | https://books.google.ru/books?id=jglFsz5EJR8C&pg=PA439&lpg=PA439&dq=AMOLANONE retrieved from Drug Discovery: A History By Walter Sneader, p.439

Amolanone (amethone) is a local anesthetic. It also has antispasmodic action.

Approval Year

Sourcing

Vendor/Aggregator	ID	URL
001 Chemical	DY570626	https://www.001chemical.com/chem/76-65-3
AAA Chemistry	AR-1F0903
ABI Chem	AC1L1MKC
ABI Chem	AC1Q2Z9P
ABI Chem	AC1Q6MLF
Alfa Chemistry	76-65-3	https://www.alfa-chemistry.com/cas_76-65-3.htm
Chemieliva Pharmaceutical Co., Ltd	PBCM1411778
ChemMol	99147258	http://www.chemmol.com/chemmol/99147258.html
ChemTik	CTK5B0981
eMolecules	38888
Molcore	MC570626	https://www.molcore.com/product/76-65-3
NovoSeek	6453
Smolecule	S518732	http://www.smolecule.com/products/s518732
THE BioTek	bt-259660	https://www.thebiotek.com/product/inhibitors/bt-259660
ZINC	ZINC000006720796	http://zinc15.docking.org/substances/ZINC000006720796
ZINC	ZINC000053021878	http://zinc15.docking.org/substances/ZINC000053021878

PubMed

Title	Date	PubMed
Studies in urethral anesthesia: tronothane and amethone.	1957	13496207

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:00:19 GMT 2025` Edited by `admin` on `Mon Mar 31 18:00:19 GMT 2025`
Record UNII	M36927R46E
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

AMOLANONE HYDROCHLORIDE

Common Name

English

AMETHONE HYDROCHLORIDE

Preferred Name

English

AMOLANONE HCL

Common Name

English

3-(2-(DIETHYLAMINO)ETHYL)-3-PHENYL-2(3H)-BENZOFURANONE HYDROCHLORIDE

Systematic Name

English

2(3H)-BENZOFURANONE, 3-(2-(DIETHYLAMINO)ETHYL)-3-PHENYL-, HYDROCHLORIDE (1:1)

Systematic Name

English

AMOLANONE HYDROCHLORIDE [MI]

Common Name

English

2(3H)-BENZOFURANONE, 3-(2-(DIETHYLAMINO)ETHYL)-3-PHENYL-, HYDROCHLORIDE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C245