PLONMARLIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 00:07:06 GMT 2025` Edited by `admin` on `Wed Apr 02 00:07:06 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	M1K0A3X96W
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TJ003234

Preferred Name

English

PLONMARLIMAB

Official Name

English

Plonmarlimab [WHO-DD]

Common Name

English

plonmarlimab [INN]

Common Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR) (HUMAN MONOCLONAL TJ003234 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL TJ003234 .KAPPA.-CHAIN, DIMER

Common Name

English

TJ003234 (ANTI-GM-CSF MONOCLONAL ANTIBODY)

Common Name

English

TJM-2

Code

English

TJ-003234

Code

English

Code System Code Type Description

SMS_ID

300000025379

Created by admin on Wed Apr 02 00:07:06 GMT 2025 , Edited by admin on Wed Apr 02 00:07:06 GMT 2025

PRIMARY

NCI_THESAURUS

C172653

Created by admin on Wed Apr 02 00:07:06 GMT 2025 , Edited by admin on Wed Apr 02 00:07:06 GMT 2025

PRIMARY

FDA UNII

M1K0A3X96W

Created by admin on Wed Apr 02 00:07:06 GMT 2025 , Edited by admin on Wed Apr 02 00:07:06 GMT 2025

PRIMARY

INN

11595

Created by admin on Wed Apr 02 00:07:06 GMT 2025 , Edited by admin on Wed Apr 02 00:07:06 GMT 2025

PRIMARY

INN

CAS

2377482-36-3

Created by admin on Wed Apr 02 00:07:06 GMT 2025 , Edited by admin on Wed Apr 02 00:07:06 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_147	2_203
2_223	4_214
2_264	2_324
1_147	1_203
2_370	2_428
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_223	3_214
1_229	2_229
1_232	2_232
1_264	1_324
1_370	1_428

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_300
N	2_300

Related Record Type Details


					KIJ28K7WXF

GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR HUMAN

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					M1K0A3X96W

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS		Amount:	PIDOLIC ACID	SZB83O1W42
AMINO ACID REMOVAL	[1_450] [2_450]	C-TERMINUS			LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL