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Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Wed Apr 02 00:07:06 GMT 2025
Edited
by admin
on Wed Apr 02 00:07:06 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
M1K0A3X96W
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TJ003234
Preferred Name English
PLONMARLIMAB
INN  
Official Name English
Plonmarlimab [WHO-DD]
Common Name English
plonmarlimab [INN]
Common Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR) (HUMAN MONOCLONAL TJ003234 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL TJ003234 .KAPPA.-CHAIN, DIMER
Common Name English
TJ003234 (ANTI-GM-CSF MONOCLONAL ANTIBODY)
Common Name English
TJM-2
Code English
TJ-003234
Code English
Code System Code Type Description
SMS_ID
300000025379
Created by admin on Wed Apr 02 00:07:06 GMT 2025 , Edited by admin on Wed Apr 02 00:07:06 GMT 2025
PRIMARY
NCI_THESAURUS
C172653
Created by admin on Wed Apr 02 00:07:06 GMT 2025 , Edited by admin on Wed Apr 02 00:07:06 GMT 2025
PRIMARY
FDA UNII
M1K0A3X96W
Created by admin on Wed Apr 02 00:07:06 GMT 2025 , Edited by admin on Wed Apr 02 00:07:06 GMT 2025
PRIMARY
INN
11595
Created by admin on Wed Apr 02 00:07:06 GMT 2025 , Edited by admin on Wed Apr 02 00:07:06 GMT 2025
PRIMARY INN
CAS
2377482-36-3
Created by admin on Wed Apr 02 00:07:06 GMT 2025 , Edited by admin on Wed Apr 02 00:07:06 GMT 2025
PRIMARY
From To
1_22 1_96
2_22 2_96
2_147 2_203
2_223 4_214
2_264 2_324
1_147 1_203
2_370 2_428
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
1_223 3_214
1_229 2_229
1_232 2_232
1_264 1_324
1_370 1_428
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_300
N 2_300
Related Record Type Details
GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR HUMAN
TARGET -> INHIBITOR
Related Record Type Details
PLONMARLIMAB
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
AMINO_ACID_SUBSTITUTION [1_1] [2_1] N-TERMINUS Amount: PIDOLIC ACID SZB83O1W42
AMINO ACID REMOVAL [1_450] [2_450] C-TERMINUS LYSINE K3Z4F929H6
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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