Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 15:40:51 UTC 2023
by
admin
on
Sat Dec 16 15:40:51 UTC 2023
|
| Protein Type | BISPECIFIC ANTIBODY |
| Protein Sub Type | chimeric-fusion|IGG1 |
| Sequence Origin | MOUSE CHIMERIC (CETUXIMAB), HUMAN (TGFBR2-ECD) |
| Sequence Type | COMPLETE |
| Record UNII |
LZ88YF62H2
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Official Name | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Code | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
12962
Created by
admin on Sat Dec 16 15:40:52 UTC 2023 , Edited by admin on Sat Dec 16 15:40:52 UTC 2023
|
PRIMARY | |||
|
LZ88YF62H2
Created by
admin on Sat Dec 16 15:40:52 UTC 2023 , Edited by admin on Sat Dec 16 15:40:52 UTC 2023
|
PRIMARY | |||
|
2764727-44-6
Created by
admin on Sat Dec 16 15:40:52 UTC 2023 , Edited by admin on Sat Dec 16 15:40:52 UTC 2023
|
PRIMARY | |||
|
KL-248
Created by
admin on Sat Dec 16 15:40:52 UTC 2023 , Edited by admin on Sat Dec 16 15:40:52 UTC 2023
|
PRIMARY | |||
|
C173165
Created by
admin on Sat Dec 16 15:40:52 UTC 2023 , Edited by admin on Sat Dec 16 15:40:52 UTC 2023
|
PRIMARY |
| From | To |
|---|---|
| 1_22 | 1_95 |
| 1_146 | 1_202 |
| 1_222 | 3_214 |
| 1_228 | 2_228 |
| 1_231 | 2_231 |
| 1_263 | 1_323 |
| 1_369 | 1_427 |
| 2_22 | 2_95 |
| 2_146 | 2_202 |
| 2_222 | 4_214 |
| 2_263 | 2_323 |
| 2_369 | 2_427 |
| 3_23 | 3_88 |
| 3_134 | 3_194 |
| 3_258 | 3_261 |
| 3_268 | 3_274 |
| 3_278 | 3_284 |
| 3_291 | 3_308 |
| 3_328 | 3_343 |
| 3_345 | 3_350 |
| 4_23 | 4_88 |
| 4_134 | 4_194 |
| 4_258 | 4_261 |
| 4_268 | 4_274 |
| 4_278 | 4_284 |
| 4_291 | 4_308 |
| 4_328 | 4_343 |
| 4_345 | 4_350 |
| Glycosylation Type | MAMMALIAN |
| Glycosylation Link Type | Site |
|---|---|
| N | 1_88 |
| N | 1_299 |
| N | 2_88 |
| N | 2_299 |
| N | 3_277 |
| N | 3_301 |
| N | 3_361 |
| N | 4_277 |
| N | 4_301 |
| N | 4_361 |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
CONJUGATE COMPONENT->CONJUGATE |
|
||
|
|
TARGET -> INHIBITOR |
By mopping up active TGF beta, FmAb2 inhibits TGFβ signaling pathways
|
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
ACTIVE MOIETY |
advanced/metastatic malignancies including colorectal cancer
|
| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT:NUMBER AVERAGE | CHEMICAL |
|
||||
| Molecular Formula | CHEMICAL |
|
||||
| MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
|