TEROXALENE HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C28H41ClN2O.ClH
Molecular Weight	493.552
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CCC(C)(C)C1=CC=C(OCCCCCCN2CCN(CC2)C3=CC(Cl)=C(C)C=C3)C=C1

InChI

InChIKey=GWLHCTMTLJQQKG-UHFFFAOYSA-N

InChI=1S/C28H41ClN2O.ClH/c1-5-28(3,4)24-11-14-26(15-12-24)32-21-9-7-6-8-16-30-17-19-31(20-18-30)25-13-10-23(2)27(29)22-25;/h10-15,22H,5-9,16-21H2,1-4H3;1H

HIDE SMILES / InChI

Molecular Formula	C28H41ClN2O
Molecular Weight	457.091
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/8070010 | https://www.ncbi.nlm.nih.gov/pubmed/11087578

Teroxalene is a dioxopiperazine derivative with multidrug resistance reversal activity

Originator

Approval Year

PubMed

Title	Date	PubMed
Reversal of multidrug resistance by bis(phenylalkyl)amines and structurally related compounds.	1994	8070010

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:04:15 GMT 2023` Edited by `admin` on `Fri Dec 15 15:04:15 GMT 2023`
Record UNII	LYL9ES50QE
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TEROXALENE HYDROCHLORIDE

Official Name

English

TEROXALENE HYDROCHLORIDE [USAN]

Common Name

English

NSC-138704

Code

English

A-16612

Code

English

PR-3847

Code

English

PIPERAZINE, 1-(3-CHLORO-4-METHYLPHENYL)-4-(6-(4-(1,1-DIMETHYLPROPYL)PHENOXY)HEXYL)-, MONOHYDROCHLORIDE

Common Name

English

1-(3-CHLORO-P-TOLYL)-4-(6-(P-TERT-PENTYLPHENOXY)HEXYL)PIPERAZINE MONOHYDROCHLORIDE

Common Name

English

TEROXALENE HCL

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C250