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Details

Stereochemistry ABSOLUTE
Molecular Formula C20H17NO6
Molecular Weight 367.3521
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CAPNOIDINE

SMILES

[H][C@]1(OC(=O)C2=C1C=CC3=C2OCO3)[C@]4([H])N(C)CCC5=C4C=C6OCOC6=C5

InChI

InChIKey=IYGYMKDQCDOMRE-QZTJIDSGSA-N
InChI=1S/C20H17NO6/c1-21-5-4-10-6-14-15(25-8-24-14)7-12(10)17(21)18-11-2-3-13-19(26-9-23-13)16(11)20(22)27-18/h2-3,6-7,17-18H,4-5,8-9H2,1H3/t17-,18-/m1/s1

HIDE SMILES / InChI
Molecular Formula C20H17NO6
Molecular Weight 367.3521
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

CAPNOIDINE an alkaloid found in the climbing fumitory. CAPNOIDINE shows no antiplasmodial in K1CB1 a multidrug resistant P. falciparum strain and in TM4/8.2, a wild type chloroquine and antifolate sensitive P. falciparum strain

Originator

Approval Year

Unknown
139594
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Isolation and chemistry of alkaloids from plants of the family Papaveraceae LXVII: Corydalis cava (L.) Sch. et K. (C. tuberosa DC).
1976 Feb
Antimalarial alkaloids from a Bhutanese traditional medicinal plant Corydalis dubia.
2012 Aug 30

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
CAPNOIDINE shows no antiplasmodial in K1CB1 a multidrug resistant P. falciparum strain and in TM4/8.2, a wild type chloroquine and antifolate sensitive P. falciparum strain
Substance Class Chemical
Created
by admin
on Sat Dec 16 10:58:22 GMT 2023
Edited
by admin
on Sat Dec 16 10:58:22 GMT 2023
Record UNII
LV8QH3HB1R
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CAPNOIDINE
Common Name English
L-ADLUMIDINE
MI  
Common Name English
ADLUMIDINE, (-)-
Common Name English
FURO(3,4-E)-1,3-BENZODIOXOL-8(6H)-ONE, 6-((5R)-5,6,7,8-TETRAHYDRO-6-METHYL-1,3-DIOXOLO(4,5-G)ISOQUINOLIN-5-YL)-, (6R)-
Systematic Name English
L-CAPNOIDINE
Common Name English
(-)-ADLUMIDINE
Common Name English
(-)-CAPNOIDINE
Common Name English
L-ADLUMIDINE [MI]
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID80197543
Created by admin on Sat Dec 16 10:58:22 GMT 2023 , Edited by admin on Sat Dec 16 10:58:22 GMT 2023
PRIMARY
PUBCHEM
120698
Created by admin on Sat Dec 16 10:58:22 GMT 2023 , Edited by admin on Sat Dec 16 10:58:22 GMT 2023
PRIMARY
FDA UNII
LV8QH3HB1R
Created by admin on Sat Dec 16 10:58:22 GMT 2023 , Edited by admin on Sat Dec 16 10:58:22 GMT 2023
PRIMARY
CAS
485-50-7
Created by admin on Sat Dec 16 10:58:22 GMT 2023 , Edited by admin on Sat Dec 16 10:58:22 GMT 2023
PRIMARY
NIH
NCATS
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