Macitegtagene autoleucel transgene insert

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Wed Apr 02 20:16:27 GMT 2025` Edited by `admin` on `Wed Apr 02 20:16:27 GMT 2025`
Nucleic Acid Type	VECTOR
Sequence Origin	VIRAL, HUMAN
Sequence Type	COMPLETE
Record UNII	LV296BSH6N
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Macitegtagene autoleucel transgene insert encoding a a chimeric antigen receptor (CAR) targeting the intercellular adhesion molecule-1 (ICAM-1) fused to human somatostatin receptor type 2 (SSTR2), under control of the human elongation factor-1 alpha (EF-

Preferred Name

English

Macitegtagene autoleucel transgene insert

Common Name

English

Code System Code Type Description

FDA UNII

LV296BSH6N

Created by admin on Wed Apr 02 20:16:27 GMT 2025 , Edited by admin on Wed Apr 02 20:16:27 GMT 2025

PRIMARY

Sugar	Site Range	Site Count
Deoxyribose (DNA)	1_1-1_6720	6720 / 6720

Linkage	Site Range	Site Count
Phosphate	1_2-1_6720	6719 / 6719

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
qPCR ID Tag	NUCLEIC ACID FEATURE

Viral packaging signal	NUCLEIC ACID FEATURE

ORF	NUCLEIC ACID FEATURE

cPPT/CTS	NUCLEIC ACID FEATURE

WPRE	NUCLEIC ACID FEATURE

3'sinLTR	NUCLEIC ACID FEATURE

5'LTR (R-U5)	NUCLEIC ACID FEATURE

EF1? promoter	NUCLEIC ACID FEATURE