BORNELONE

US Previously Marketed

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2721377

Bornelone (also known as Bornelon) is used as ultraviolet (UV) absorber, in order to protect include cosmetic products against the influence of ultraviolet light. Bornelone is not allowed as a UV filter in sunscreens in the Europe, as it was discovered, that in contact with the skin contact dermatitis could cause.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Ultraviolet (UV) 1 Target ID: Ultraviolet (UV) Sources: https://www.ncbi.nlm.nih.gov/pubmed/2721377	Binding Agent 1076

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2596

Doses

Dose	Population	Adverse events
1 % multiple, topical Studied dose Dose: 1 % Route: topical Route: multiple Dose: 1 % Sources: https://pubmed.ncbi.nlm.nih.gov/6705520/	healthy, mean age 48.5 years Health Status: healthy Age Group: mean age 48.5 years Sex: F Sources: https://pubmed.ncbi.nlm.nih.gov/6705520/	Other AEs: Allergic contact dermatitis... Other AEs: Allergic contact dermatitis Sources: https://pubmed.ncbi.nlm.nih.gov/6705520/

AEs

AE	Significance	Dose	Population
Allergic contact dermatitis		1 % multiple, topical Studied dose Dose: 1 % Route: topical Route: multiple Dose: 1 % Sources: https://pubmed.ncbi.nlm.nih.gov/6705520/	healthy, mean age 48.5 years Health Status: healthy Age Group: mean age 48.5 years Sex: F Sources: https://pubmed.ncbi.nlm.nih.gov/6705520/

Sourcing

Vendor/Aggregator	ID	URL
BOC Sciences	119375
Chemspace	CSC020618295
Chemspace	CSC020667366
Chemspace	CSC042324788
Compound Cloud	6436059
Enamine	BBV-45114535
Enamine	BBV-78228517
Enamine	BBV-98680205
Norris Pharm	NSZB-A218977
Tetrahedron	TS19820
ZINC	ZINC000100072972	http://zinc15.docking.org/substances/ZINC000100072972
ZINC	ZINC000136377589	http://zinc15.docking.org/substances/ZINC000136377589

PubMed

Title	Date	PubMed
Cosmetic allergy to the UV-absorber bornelone.	1989-01-01	2721377
Contact allergy to bornelone.	1984-01	6705520

Patents

Sample Use Guides

In Vivo Use Guide

sunscreen

Route of Administration: Topical

In Vitro Use Guide

Unknown

Substance Class	Mixture Created by `admin` on `Wed Apr 02 20:23:43 GMT 2025` Edited by `admin` on `Wed Apr 02 20:23:43 GMT 2025`
Record UNII	LU86E5P72A
Record Status	`FAILED`
Record Version

Download

Name

Type

Language

bornelone [INN]

Preferred Name

English

BORNELONE

Official Name

English

5-(3,3-Dimethyl-2-norbornylidene)-3-penten-2-one

Systematic Name

English

5(3,3-DIMETHYL-2-NORBORNYLIDENE)-3 PENTENE-2-ONE

Systematic Name

English

BORNELONE [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C851