BEMITRADINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C15H17N5O
Molecular Weight	283.3284
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOCCC1=C(N=C(N)N2N=CN=C12)C3=CC=CC=C3

InChI

InChIKey=OZSPQIXKOVJJGE-UHFFFAOYSA-N

InChI=1S/C15H17N5O/c1-2-21-9-8-12-13(11-6-4-3-5-7-11)19-15(16)20-14(12)17-10-18-20/h3-7,10H,2,8-9H2,1H3,(H2,16,19)

HIDE SMILES / InChI

Molecular Formula	C15H17N5O
Molecular Weight	283.3284
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1629511 | https://www.ncbi.nlm.nih.gov/pubmed/3245233

Bemitradine (SC-33643), a diuretic antihypertensive agent that was dropped from the development. Experiments on rodents have revealed this drug was a carcinogen and acted by a hormonally modulated promotional activity in inducing tumors in the liver and mammary glands.

Approval Year

PubMed

Title	Date	PubMed

Patents

Sample Use Guides

In Vivo Use Guide

Bemitradine (50 mg) was rapidly and efficiently absorbed (approximately 89%) in man following a single oral dose, as a solution in gelatine capsules.

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:31:04 GMT 2023` Edited by `admin` on `Fri Dec 15 15:31:04 GMT 2023`
Record UNII	LT9004D9N0
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BEMITRADINE

Official Name

English

SC-33643

Code

English

5-Amino-8-(2-ethoxyethyl)-7-phenyl-S-triazolo[1,5-c]pyrimidine

Systematic Name

English

bemitradine [INN]

Common Name

English

(1,2,4)TRIAZOLO(1,5-C)PYRIMIDIN-5-AMINE, 8-(2-ETHOXYETHYL)-7-PHENYL-

Systematic Name

English

BEMITRADINE [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C448