VINEPIDINE SULFATE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C46H56N4O9.H2O4S
Molecular Weight	907.037
Optical Activity	UNSPECIFIED
Defined Stereocenters	9 / 9
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OS(O)(=O)=O.[H][C@@]12N3CC[C@@]14C5=C(C=C(OC)C(=C5)[C@]6(C[C@]7([H])C[C@H](CC)CN(C7)CCC8=C6NC9=CC=CC=C89)C(=O)OC)N(C=O)[C@@]4([H])[C@](O)([C@H](OC(C)=O)[C@]2(CC)C=CC3)C(=O)OC

InChI

InChIKey=BCXOZISMDZTYHW-IFQBWSDRSA-N

InChI=1S/C46H56N4O9.H2O4S/c1-7-28-20-29-23-45(41(53)57-5,37-31(14-18-48(24-28)25-29)30-12-9-10-13-34(30)47-37)33-21-32-35(22-36(33)56-4)50(26-51)39-44(32)16-19-49-17-11-15-43(8-2,38(44)49)40(59-27(3)52)46(39,55)42(54)58-6;1-5(2,3)4/h9-13,15,21-22,26,28-29,38-40,47,55H,7-8,14,16-20,23-25H2,1-6H3;(H2,1,2,3,4)/t28-,29-,38-,39+,40+,43+,44+,45-,46-;/m0./s1

HIDE SMILES / InChI

Molecular Formula	H2O4S
Molecular Weight	98.078
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C46H56N4O9
Molecular Weight	808.9582
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	8 / 9
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3986806 | Brossi Arnold, Suffness Matthew, The Alkaloids: Antitumor Bisindole Alkaloids from Catharanthus roseus (L.), p. 190, retrieved from:https://books.google.ru/books?id=EcrtXS98DLoC&pg=PA190&lpg=PA190&dq=VINEPIDINE&source=bl&ots=e86Vcx4c24&sig=ACfU3U1CJyzl_lf70nu-Tebn0ZUu_r2WIg&hl=ru&sa=X&ved=2ahUKEwjCkY3NpKvjAhVH06YKHSL4A284ChDoATAAegQIBxAB#v=onepage&q=VINEPIDINE&f=false

Vinepidine, a derivative of vincristine participated in clinical trials as an antineoplastic agent. As a result, the extreme neuromuscular toxicity was observed, that is why this study was discontinued.

Approval Year

PubMed

Title	Date	PubMed

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Intravenous

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:01:29 GMT 2023` Edited by `admin` on `Fri Dec 15 17:01:29 GMT 2023`
Record UNII	LS5489G27S
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

VINEPIDINE SULFATE

Official Name

English

VINEPIDINE SULPHATE

Common Name

English

LY 119863

Code

English

(4'S)-4'-DEOXYLEUROCRISTINE SULPHATE (1:1)

Common Name

English

LY-119863

Code

English

(4'S)-4'-DEOXYLEUROCRISTINE SULFATE (1:1)

Common Name

English

VINEPIDINE SULFATE [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C932