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Details

Stereochemistry ABSOLUTE
Molecular Formula C22H20N2O4
Molecular Weight 376.4052
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 7-ETHYLCAMPTOTHECIN

SMILES

CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC5=CC=CC=C15

InChI

InChIKey=MYQKIWCVEPUPIL-QFIPXVFZSA-N
InChI=1S/C22H20N2O4/c1-3-12-13-7-5-6-8-17(13)23-19-14(12)10-24-18(19)9-16-15(20(24)25)11-28-21(26)22(16,27)4-2/h5-9,27H,3-4,10-11H2,1-2H3/t22-/m0/s1

HIDE SMILES / InChI

Molecular Formula C22H20N2O4
Molecular Weight 376.4052
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
4.44 µM [EC50]
PubMed

PubMed

TitleDatePubMed
Substance Class Chemical
Created
by admin
on Fri Jul 07 00:18:17 UTC 2023
Edited
by admin
on Fri Jul 07 00:18:17 UTC 2023
Record UNII
LPY7FE51IW
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
7-ETHYLCAMPTOTHECIN
Common Name English
1H-PYRANO(3',4':6,7)INDOLIZINO(1,2-B)QUINOLINE-3,14(4H,12H)-DIONE, 4,11-DIETHYL-4-HYDROXY-, (4S)-
Systematic Name English
7-ETHYLCAMPTOTHECIN [USP IMPURITY]
Common Name English
1H-PYRANO(3',4':6,7)INDOLIZINO(1,2-B)QUINOLINE-3,14(4H,12H)-DIONE, 4,11-DIETHYL-4-HYDROXY-, (S)-
Systematic Name English
7-ETHYL-20(S)-CAMPTOTHECIN
Common Name English
IRINOTECAN RELATED COMPOUND E [USP-RS]
Common Name English
SN 22
Common Name English
(S)-4,11-DIETHYL-4-HYDROXY-1H-PYRANO(3,4:6,7)INDOLIZINO(1,2-B)QUIN OLINE-3,14(4H,12H)-DIONE
Systematic Name English
Code System Code Type Description
EPA CompTox
DTXSID60228960
Created by admin on Fri Jul 07 00:18:18 UTC 2023 , Edited by admin on Fri Jul 07 00:18:18 UTC 2023
PRIMARY
RS_ITEM_NUM
1347664
Created by admin on Fri Jul 07 00:18:18 UTC 2023 , Edited by admin on Fri Jul 07 00:18:18 UTC 2023
PRIMARY
FDA UNII
LPY7FE51IW
Created by admin on Fri Jul 07 00:18:18 UTC 2023 , Edited by admin on Fri Jul 07 00:18:18 UTC 2023
PRIMARY
PUBCHEM
127584
Created by admin on Fri Jul 07 00:18:18 UTC 2023 , Edited by admin on Fri Jul 07 00:18:18 UTC 2023
PRIMARY
CAS
78287-27-1
Created by admin on Fri Jul 07 00:18:18 UTC 2023 , Edited by admin on Fri Jul 07 00:18:18 UTC 2023
PRIMARY
Related Record Type Details
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP