Approval Year
| Substance Class |
Concept
|
| Record UNII |
LPT9GX4OUB
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Code | English | ||
|
Code | English | ||
|
Common Name | English | ||
|
Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
NCI_THESAURUS |
C20401
Created by
admin on Sat Dec 16 14:19:49 GMT 2023 , Edited by admin on Sat Dec 16 14:19:49 GMT 2023
|
||
|
NCI_THESAURUS |
C129822
Created by
admin on Sat Dec 16 14:19:49 GMT 2023 , Edited by admin on Sat Dec 16 14:19:49 GMT 2023
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
C101521
Created by
admin on Sat Dec 16 14:19:49 GMT 2023 , Edited by admin on Sat Dec 16 14:19:49 GMT 2023
|
PRIMARY | NCIT | ||
|
LPT9GX4OUB
Created by
admin on Sat Dec 16 14:19:49 GMT 2023 , Edited by admin on Sat Dec 16 14:19:49 GMT 2023
|
PRIMARY |
This is a non-substance concept
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
TARGET -> INHIBITOR |
Specifically binds to DLL4 and prevents its interaction with Notch receptors, thereby inhibiting Notch-mediated signaling and gene transcription, which may block tumor angiogenesis and eventually the inhibition of tumor cell growth.
|
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
ACTIVE MOIETY |
This is a non-substance concept